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Segmental action of morphine and acupuncture-like stimulation in the dorsal horn of the rat as visualized by the 14C-2-deoxyglucose method

Sjolund, B. H. and Schouenborg, J. LU (1980) In Neuroscience Letters 19(SUPPL. 5). p.107-107
Abstract

It is not clear where analgesic measures such as morphine and acupuncture have their sites of action. Since analgesia from acupuncturelike stimulation is reversed by naloxone (Sjolund and Eriksson, Brain Res. 173:295, 1979) it is probably mediated via endorphins. The two analgesic procedures mentioned may thus use similar inhibitory mechanisms. We now present data from autoradiographic measurements of regional 'nervous' activity (Sokoloff et al., J. Neurochem., 28:897, 1977) in the rat spinal cord, indicating that the inhibition is present already in the outer dorsal horn laminae.

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author
and
organization
publishing date
type
Contribution to journal
publication status
published
in
Neuroscience Letters
volume
19
issue
SUPPL. 5
pages
107 - 107
publisher
Elsevier
external identifiers
  • scopus:0019121877
ISSN
0304-3940
language
English
LU publication?
yes
id
6b49d45b-88cc-4461-bb11-1ae622731d53
date added to LUP
2019-06-25 16:15:29
date last changed
2021-01-03 08:00:49
@article{6b49d45b-88cc-4461-bb11-1ae622731d53,
  abstract     = {{<p>It is not clear where analgesic measures such as morphine and acupuncture have their sites of action. Since analgesia from acupuncturelike stimulation is reversed by naloxone (Sjolund and Eriksson, Brain Res. 173:295, 1979) it is probably mediated via endorphins. The two analgesic procedures mentioned may thus use similar inhibitory mechanisms. We now present data from autoradiographic measurements of regional 'nervous' activity (Sokoloff et al., J. Neurochem., 28:897, 1977) in the rat spinal cord, indicating that the inhibition is present already in the outer dorsal horn laminae.</p>}},
  author       = {{Sjolund, B. H. and Schouenborg, J.}},
  issn         = {{0304-3940}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{SUPPL. 5}},
  pages        = {{107--107}},
  publisher    = {{Elsevier}},
  series       = {{Neuroscience Letters}},
  title        = {{Segmental action of morphine and acupuncture-like stimulation in the dorsal horn of the rat as visualized by the 14C-2-deoxyglucose method}},
  volume       = {{19}},
  year         = {{1980}},
}