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How deaths of despair shape life expectancy across sexes and regions in Sweden

Kiadaliri, Ali LU orcid ; Cullen, Alexis E ; Plana-Ripoll, Oleguer and Hajizadeh, Mohammad (2026) In Scandinavian Journal of Public Health
Abstract

AIM: The sim of this study was to quantify contributions of mortality from drugs, alcohol and suicide (termed as 'deaths of despair' (DoD)) to changes in life expectancy at birth across sexes and regions in Sweden.

METHODS: We obtained annual data on underlying causes of deaths by age, sex and region from the National Cause of Death Register. We constructed abridged life tables for two periods: 2001-2005 and 2020-2024. A continuous-change model was used to quantify the age- and cause-specific contributions of DoD to the changes in life expectancy at birth between these periods.

RESULTS: Between two periods, life expectancy at birth increased by 2.5/3.5 years for females/males. All three DoD combined had negligible but... (More)

AIM: The sim of this study was to quantify contributions of mortality from drugs, alcohol and suicide (termed as 'deaths of despair' (DoD)) to changes in life expectancy at birth across sexes and regions in Sweden.

METHODS: We obtained annual data on underlying causes of deaths by age, sex and region from the National Cause of Death Register. We constructed abridged life tables for two periods: 2001-2005 and 2020-2024. A continuous-change model was used to quantify the age- and cause-specific contributions of DoD to the changes in life expectancy at birth between these periods.

RESULTS: Between two periods, life expectancy at birth increased by 2.5/3.5 years for females/males. All three DoD combined had negligible but opposite contributions to the changes in life expectancy at birth among females (-0.017 years) and males (+0.101 years). In both sexes, drugs- (alcohol)-related deaths contributed to decrease (increase) in life expectancy at birth. In both sexes, deaths from suicide in the age group 10-19 years (negative contributions), drugs in the age group 30-39 years (negative contributions) and alcohol in the age groups 40-59 years (positive contributions) and 70-89 years (negative contributions) had a greater absolute contribution to the changes in life expectancy at birth than the other two DoD causes. Across regions, the changes in life expectancy at birth attributable to DoD ranged from -0.219 to +0.159 years among females and from -0.235 to +0.267 years among males.

CONCLUSIONS: There were large variations in the contributions of DoD to the change in life expectancy at birth by age, sex, cause and region in Sweden, highlighting the need for targeted national and regional interventions, especially for drug-related deaths.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
in
Scandinavian Journal of Public Health
publisher
SAGE Publications
external identifiers
  • scopus:105040394003
  • pmid:42212761
ISSN
1651-1905
DOI
10.1177/14034948261450785
language
English
LU publication?
yes
id
6f75ae20-ff48-4bb6-ad3c-ba24ea91a68c
date added to LUP
2026-08-08 11:28:59
date last changed
2026-09-16 14:11:01
@article{6f75ae20-ff48-4bb6-ad3c-ba24ea91a68c,
  abstract     = {{<p>AIM: The sim of this study was to quantify contributions of mortality from drugs, alcohol and suicide (termed as 'deaths of despair' (DoD)) to changes in life expectancy at birth across sexes and regions in Sweden.</p><p>METHODS: We obtained annual data on underlying causes of deaths by age, sex and region from the National Cause of Death Register. We constructed abridged life tables for two periods: 2001-2005 and 2020-2024. A continuous-change model was used to quantify the age- and cause-specific contributions of DoD to the changes in life expectancy at birth between these periods.</p><p>RESULTS: Between two periods, life expectancy at birth increased by 2.5/3.5 years for females/males. All three DoD combined had negligible but opposite contributions to the changes in life expectancy at birth among females (-0.017 years) and males (+0.101 years). In both sexes, drugs- (alcohol)-related deaths contributed to decrease (increase) in life expectancy at birth. In both sexes, deaths from suicide in the age group 10-19 years (negative contributions), drugs in the age group 30-39 years (negative contributions) and alcohol in the age groups 40-59 years (positive contributions) and 70-89 years (negative contributions) had a greater absolute contribution to the changes in life expectancy at birth than the other two DoD causes. Across regions, the changes in life expectancy at birth attributable to DoD ranged from -0.219 to +0.159 years among females and from -0.235 to +0.267 years among males.</p><p>CONCLUSIONS: There were large variations in the contributions of DoD to the change in life expectancy at birth by age, sex, cause and region in Sweden, highlighting the need for targeted national and regional interventions, especially for drug-related deaths.</p>}},
  author       = {{Kiadaliri, Ali and Cullen, Alexis E and Plana-Ripoll, Oleguer and Hajizadeh, Mohammad}},
  issn         = {{1651-1905}},
  language     = {{eng}},
  month        = {{05}},
  publisher    = {{SAGE Publications}},
  series       = {{Scandinavian Journal of Public Health}},
  title        = {{How deaths of despair shape life expectancy across sexes and regions in Sweden}},
  url          = {{http://dx.doi.org/10.1177/14034948261450785}},
  doi          = {{10.1177/14034948261450785}},
  year         = {{2026}},
}