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Biosensing using arrays of vertical semiconductor nanowires : mechanosensing and biomarker detection

Lard, Mercy LU ; Linke, Heiner LU orcid and Prinz, Christelle N. LU (2019) In Nanotechnology 30(21).
Abstract

Due to their high aspect ratio and increased surface-to-foot-print area, arrays of vertical semiconductor nanowires are used in numerous biological applications, such as cell transfection and biosensing. Here we focus on two specific valuable biosensing approaches that, so far, have received relatively limited attention in terms of their potential capabilities: cellular mechanosensing and lightguiding-induced enhanced fluorescence detection. Although proposed a decade ago, these two applications for using vertical nanowire arrays have only very recently achieved significant breakthroughs, both in terms of understanding their fundamental phenomena, and in the ease of their implementation. We review the status of the field in these areas... (More)

Due to their high aspect ratio and increased surface-to-foot-print area, arrays of vertical semiconductor nanowires are used in numerous biological applications, such as cell transfection and biosensing. Here we focus on two specific valuable biosensing approaches that, so far, have received relatively limited attention in terms of their potential capabilities: cellular mechanosensing and lightguiding-induced enhanced fluorescence detection. Although proposed a decade ago, these two applications for using vertical nanowire arrays have only very recently achieved significant breakthroughs, both in terms of understanding their fundamental phenomena, and in the ease of their implementation. We review the status of the field in these areas and describe significant findings and potential future directions.

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Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nanotechnology
volume
30
issue
21
article number
214003
publisher
IOP Publishing
external identifiers
  • scopus:85063294944
  • pmid:30699399
ISSN
0957-4484
DOI
10.1088/1361-6528/ab0326
language
English
LU publication?
yes
id
778e89cb-9a55-48f3-9e17-d8635c7b9547
date added to LUP
2019-04-01 14:30:35
date last changed
2024-05-14 04:54:53
@article{778e89cb-9a55-48f3-9e17-d8635c7b9547,
  abstract     = {{<p>Due to their high aspect ratio and increased surface-to-foot-print area, arrays of vertical semiconductor nanowires are used in numerous biological applications, such as cell transfection and biosensing. Here we focus on two specific valuable biosensing approaches that, so far, have received relatively limited attention in terms of their potential capabilities: cellular mechanosensing and lightguiding-induced enhanced fluorescence detection. Although proposed a decade ago, these two applications for using vertical nanowire arrays have only very recently achieved significant breakthroughs, both in terms of understanding their fundamental phenomena, and in the ease of their implementation. We review the status of the field in these areas and describe significant findings and potential future directions.</p>}},
  author       = {{Lard, Mercy and Linke, Heiner and Prinz, Christelle N.}},
  issn         = {{0957-4484}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{21}},
  publisher    = {{IOP Publishing}},
  series       = {{Nanotechnology}},
  title        = {{Biosensing using arrays of vertical semiconductor nanowires : mechanosensing and biomarker detection}},
  url          = {{http://dx.doi.org/10.1088/1361-6528/ab0326}},
  doi          = {{10.1088/1361-6528/ab0326}},
  volume       = {{30}},
  year         = {{2019}},
}