Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant

Amarelli, Cristiano ; Bello, Irene ; Aigner, Clemens ; Berman, Marius ; Boffini, Massimo ; Clark, Stephen ; Dalvindt, Marita LU orcid ; de Wolf, Julien ; Ensminger, Stephan and Gomez de Antonio, David , et al. (2024) In Transplant International 37.
Abstract

The machine perfusion (MP) of transplantable grafts has emerged as an upcoming field in Cardiothoracic (CT) transplantation during the last decade. This technology carries the potential to assess, preserve, and even recondition thoracic grafts before transplantation, so it is a possible game-changer in the field. This technology field has reached a critical turning point, with a growing number of publications coming predominantly from a few leading institutions, but still need solid scientific evidence. Due to the increasing need to expand the donor pool, especially in Europe, where the donor age is steeply increased, a consensus has been established to address the growing need and knowledge of machine perfusion in cardiothoracic... (More)

The machine perfusion (MP) of transplantable grafts has emerged as an upcoming field in Cardiothoracic (CT) transplantation during the last decade. This technology carries the potential to assess, preserve, and even recondition thoracic grafts before transplantation, so it is a possible game-changer in the field. This technology field has reached a critical turning point, with a growing number of publications coming predominantly from a few leading institutions, but still need solid scientific evidence. Due to the increasing need to expand the donor pool, especially in Europe, where the donor age is steeply increased, a consensus has been established to address the growing need and knowledge of machine perfusion in cardiothoracic transplantation, targeting the unmet scientific need in this growing field but also, priorities for development, and regional differences in utilization rates and organizational issues. To address MP in CT, the European Society of Organ Transplantation (ESOT) convened a dedicated Working group comprised of experts in CT to review literature about MP to develop guidelines that were subsequently discussed and voted on during the Consensus Conference that took place in person in Prague during the TLJ 3.0 in November 2022. The findings and recommendations of the Cardiothoracic Working Group on MP are presented in this article.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; ; ; ; and (Less)
author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cardio-thoracic transplantation, ex-situ heart perfusion, ex-situ lung perfusion, graft preservation, machine perfusion
in
Transplant International
volume
37
article number
13112
publisher
Springer
external identifiers
  • scopus:85211608811
  • pmid:39649067
ISSN
0934-0874
DOI
10.3389/ti.2024.13112
language
English
LU publication?
yes
id
78e07210-9676-4052-be0c-5400304310f0
date added to LUP
2025-01-27 12:14:38
date last changed
2025-01-28 03:12:15
@article{78e07210-9676-4052-be0c-5400304310f0,
  abstract     = {{<p>The machine perfusion (MP) of transplantable grafts has emerged as an upcoming field in Cardiothoracic (CT) transplantation during the last decade. This technology carries the potential to assess, preserve, and even recondition thoracic grafts before transplantation, so it is a possible game-changer in the field. This technology field has reached a critical turning point, with a growing number of publications coming predominantly from a few leading institutions, but still need solid scientific evidence. Due to the increasing need to expand the donor pool, especially in Europe, where the donor age is steeply increased, a consensus has been established to address the growing need and knowledge of machine perfusion in cardiothoracic transplantation, targeting the unmet scientific need in this growing field but also, priorities for development, and regional differences in utilization rates and organizational issues. To address MP in CT, the European Society of Organ Transplantation (ESOT) convened a dedicated Working group comprised of experts in CT to review literature about MP to develop guidelines that were subsequently discussed and voted on during the Consensus Conference that took place in person in Prague during the TLJ 3.0 in November 2022. The findings and recommendations of the Cardiothoracic Working Group on MP are presented in this article.</p>}},
  author       = {{Amarelli, Cristiano and Bello, Irene and Aigner, Clemens and Berman, Marius and Boffini, Massimo and Clark, Stephen and Dalvindt, Marita and de Wolf, Julien and Ensminger, Stephan and Gomez de Antonio, David and Hoyos, Lucas and Palmieri, Lucrezia and Schweiger, Martin and Sponga, Sandro and Wiegmann, Bettina and Neyrinck, Arne}},
  issn         = {{0934-0874}},
  keywords     = {{cardio-thoracic transplantation; ex-situ heart perfusion; ex-situ lung perfusion; graft preservation; machine perfusion}},
  language     = {{eng}},
  publisher    = {{Springer}},
  series       = {{Transplant International}},
  title        = {{European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant}},
  url          = {{http://dx.doi.org/10.3389/ti.2024.13112}},
  doi          = {{10.3389/ti.2024.13112}},
  volume       = {{37}},
  year         = {{2024}},
}