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Acute thrombo-embolic occlusion of the superior mesenteric artery. A prospective study in a well-defined population

Acosta, Stefan LU orcid and Björck, Martin (2003) In European journal of vascular and endovascular surgery 26(2). p.179-183
Abstract
Objectives: to characterize the clinical presentation of patients with acute thrombo-embolic occlusion of the superior mesenteric artery (SMA).
Design: prospective study.
Materials: twenty-four consecutive patients admitted to Blekinge County Hospital, Karlskrona, Sweden, with acute thrombo-embolic occlusion of the SMA, over a three-year period from April 1999 through March 2002.
Methods: clinical data were registered prospectively. Incidence, diagnostic procedures and factors associated with survival were analysed.
Results: the diagnosis was verified at operation in 20, and at autopsy in 4 patients. The incidence was 5.3 per 100 000 inhabitants per year. Among the 20 patients with embolic disease, atrial fibrillation was... (More)
Objectives: to characterize the clinical presentation of patients with acute thrombo-embolic occlusion of the superior mesenteric artery (SMA).
Design: prospective study.
Materials: twenty-four consecutive patients admitted to Blekinge County Hospital, Karlskrona, Sweden, with acute thrombo-embolic occlusion of the SMA, over a three-year period from April 1999 through March 2002.
Methods: clinical data were registered prospectively. Incidence, diagnostic procedures and factors associated with survival were analysed.
Results: the diagnosis was verified at operation in 20, and at autopsy in 4 patients. The incidence was 5.3 per 100 000 inhabitants per year. Among the 20 patients with embolic disease, atrial fibrillation was present in 95%, synchronous embolic events in 30% and warfarin treatment in 10%. D-dimer was elevated on admission in 13/13. Four patients were diagnosed at first consultation. Fifteen underwent curative revascularisation (6) or bowel resection only (9). Five were alive at one-year follow-up, of whom one had short bowel syndrome. Length of bowel ischaemia predicted institutional (p = 0.004) and one-year mortality (p = 0.005).
Conclusions: the incidence was higher than expected. Embolic occlusions predominated. Old age, atrial fibrillation, severe abdominal pain and synchronous embolus suggest the diagnosis of acute bowel ischaemia. Length of bowel ischaemia predicted outcome.
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author
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publishing date
type
Contribution to journal
publication status
published
subject
in
European journal of vascular and endovascular surgery
volume
26
issue
2
pages
179 - 183
publisher
Elsevier
external identifiers
  • scopus:0042244297
ISSN
1532-2165
DOI
10.1053/ejvs.2002.1893
language
English
LU publication?
no
id
7929bf0e-3377-4821-9272-808358b89fbd
date added to LUP
2020-12-14 14:38:55
date last changed
2022-03-11 06:34:36
@article{7929bf0e-3377-4821-9272-808358b89fbd,
  abstract     = {{Objectives: to characterize the clinical presentation of patients with acute thrombo-embolic occlusion of the superior mesenteric artery (SMA).<br/>Design: prospective study.<br/>Materials: twenty-four consecutive patients admitted to Blekinge County Hospital, Karlskrona, Sweden, with acute thrombo-embolic occlusion of the SMA, over a three-year period from April 1999 through March 2002.<br/>Methods: clinical data were registered prospectively. Incidence, diagnostic procedures and factors associated with survival were analysed.<br/>Results: the diagnosis was verified at operation in 20, and at autopsy in 4 patients. The incidence was 5.3 per 100 000 inhabitants per year. Among the 20 patients with embolic disease, atrial fibrillation was present in 95%, synchronous embolic events in 30% and warfarin treatment in 10%. D-dimer was elevated on admission in 13/13. Four patients were diagnosed at first consultation. Fifteen underwent curative revascularisation (6) or bowel resection only (9). Five were alive at one-year follow-up, of whom one had short bowel syndrome. Length of bowel ischaemia predicted institutional (p = 0.004) and one-year mortality (p = 0.005).<br/>Conclusions: the incidence was higher than expected. Embolic occlusions predominated. Old age, atrial fibrillation, severe abdominal pain and synchronous embolus suggest the diagnosis of acute bowel ischaemia. Length of bowel ischaemia predicted outcome.<br/>}},
  author       = {{Acosta, Stefan and Björck, Martin}},
  issn         = {{1532-2165}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{179--183}},
  publisher    = {{Elsevier}},
  series       = {{European journal of vascular and endovascular surgery}},
  title        = {{Acute thrombo-embolic occlusion of the superior mesenteric artery. A prospective study in a well-defined population}},
  url          = {{http://dx.doi.org/10.1053/ejvs.2002.1893}},
  doi          = {{10.1053/ejvs.2002.1893}},
  volume       = {{26}},
  year         = {{2003}},
}