Surface Plasmon Resonance Nanosensors for the Sensing of Bacterial Threats
(2024) p.142-176- Abstract
Microorganisms have unique biochemical mechanisms to inhibit the growth or kill other microorganisms in the same environment. Bacterial threat agents (BTA) are more effective than conventional weapons because of these characteristics, therefore, the development and production of biological weapons are still relevant. Early warning signals need to be obtained for fast and accurate detection of BTA and prevention of possible attacks. BTA identification is of great importance for government agencies, especially in military and healthcare settings. Increasing public health awareness around the world has led to the construction of reliable platforms for fast and precise detection of bioterrorism attacks. Developments in genomics,... (More)
Microorganisms have unique biochemical mechanisms to inhibit the growth or kill other microorganisms in the same environment. Bacterial threat agents (BTA) are more effective than conventional weapons because of these characteristics, therefore, the development and production of biological weapons are still relevant. Early warning signals need to be obtained for fast and accurate detection of BTA and prevention of possible attacks. BTA identification is of great importance for government agencies, especially in military and healthcare settings. Increasing public health awareness around the world has led to the construction of reliable platforms for fast and precise detection of bioterrorism attacks. Developments in genomics, biotechnology, and biochemistry have offered major revolutionary changes in the detection strategies of microorganisms. Sensitive and specific detection from mixed media is of paramount significance to avoid the spread of responsible agents. The majority of existing approaches such as microbiological, biochemical, immunological and nucleic acid-based tests are available to detect BTA. Innovative approaches in this field include aptamers, chips, and biosensor-based and on-site monitoring tools. Plasmonic sensing platforms, including Surface Plasmon Resonance (SPR) are being extended for rapid, accurate, and real-time analysis without the requirement of labeling. Besides, the sensitivity and specificity of biosensor platforms have been greatly improved by the functionalization of sensor surfaces. Afterward, it is also important to improve point-of-care systems (POCs) with low detection limits. Designing bioreceptors for target potential BTA and conducting research on packaging is expected to contribute to further studies. There are difficulties in designing an ideal platform, however, the applications of SPR-based approaches have been verified for valuable detection of BTA. In this chapter, existing and emerging technologies in the detection of BTA are discussed and the various advances in SPR sensing are summarized. The achievements in integrating proposed SPR platforms and the representative applications for the detection of BTA are examined and the challenges for rapid and accurate detection of BTA are indicated.
(Less)
- author
- I˙dil, Neslihan ; Asliyüce, Sevgi and Mattiasson, Bo LU
- organization
- publishing date
- 2024
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Plasmonic Nanosensors for Biological and Chemical Threats
- pages
- 35 pages
- publisher
- CRC Press/Balkema
- external identifiers
-
- scopus:85192456225
- ISBN
- 9781032604749
- 9781040033944
- DOI
- 10.1201/9781003459316-7
- language
- English
- LU publication?
- yes
- id
- 7e171f5d-60e0-4e02-927f-7322c58c74bb
- date added to LUP
- 2025-01-15 14:36:37
- date last changed
- 2025-07-17 05:44:28
@inbook{7e171f5d-60e0-4e02-927f-7322c58c74bb,
abstract = {{<p>Microorganisms have unique biochemical mechanisms to inhibit the growth or kill other microorganisms in the same environment. Bacterial threat agents (BTA) are more effective than conventional weapons because of these characteristics, therefore, the development and production of biological weapons are still relevant. Early warning signals need to be obtained for fast and accurate detection of BTA and prevention of possible attacks. BTA identification is of great importance for government agencies, especially in military and healthcare settings. Increasing public health awareness around the world has led to the construction of reliable platforms for fast and precise detection of bioterrorism attacks. Developments in genomics, biotechnology, and biochemistry have offered major revolutionary changes in the detection strategies of microorganisms. Sensitive and specific detection from mixed media is of paramount significance to avoid the spread of responsible agents. The majority of existing approaches such as microbiological, biochemical, immunological and nucleic acid-based tests are available to detect BTA. Innovative approaches in this field include aptamers, chips, and biosensor-based and on-site monitoring tools. Plasmonic sensing platforms, including Surface Plasmon Resonance (SPR) are being extended for rapid, accurate, and real-time analysis without the requirement of labeling. Besides, the sensitivity and specificity of biosensor platforms have been greatly improved by the functionalization of sensor surfaces. Afterward, it is also important to improve point-of-care systems (POCs) with low detection limits. Designing bioreceptors for target potential BTA and conducting research on packaging is expected to contribute to further studies. There are difficulties in designing an ideal platform, however, the applications of SPR-based approaches have been verified for valuable detection of BTA. In this chapter, existing and emerging technologies in the detection of BTA are discussed and the various advances in SPR sensing are summarized. The achievements in integrating proposed SPR platforms and the representative applications for the detection of BTA are examined and the challenges for rapid and accurate detection of BTA are indicated.</p>}},
author = {{I˙dil, Neslihan and Asliyüce, Sevgi and Mattiasson, Bo}},
booktitle = {{Plasmonic Nanosensors for Biological and Chemical Threats}},
isbn = {{9781032604749}},
language = {{eng}},
pages = {{142--176}},
publisher = {{CRC Press/Balkema}},
title = {{Surface Plasmon Resonance Nanosensors for the Sensing of Bacterial Threats}},
url = {{http://dx.doi.org/10.1201/9781003459316-7}},
doi = {{10.1201/9781003459316-7}},
year = {{2024}},
}