Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl clusters-diastereomeric control of enantioselectivity
(2020) In Dalton Transactions 49(14). p.4244-4256- Abstract
Twenty clusters of the general formula [(μ-H)2Ru3(μ3-S)(CO)7(μ-P-P∗)] (P-P∗ = chiral diphosphine of the ferrocene-based Walphos or Josiphos families) have been synthesised and characterised. The clusters have been tested as catalysts for asymmetric hydrogenation of tiglic acid [trans-2-methyl-2-butenoic acid]. The observed enantioselectivities and conversion rates strongly support catalysis by intact Ru3 clusters. A catalytic mechanism involving an active Ru3 catalyst generated by CO loss from [(μ-H)2Ru3(μ3-S)(CO)7(μ-P-P∗)] has been investigated by DFT calculations.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8138d627-1595-42c7-bbb1-c46299cfbde4
- author
- Abdel-Magied, Ahmed F. ; Theibich, Yusuf ; Singh, Amrendra K. LU ; Rahaman, Ahibur LU ; Doverbratt, Isa LU ; Raha, Arun K. LU ; Haukka, Matti ; Richmond, Michael G. and Nordlander, Ebbe LU
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Dalton Transactions
- volume
- 49
- issue
- 14
- pages
- 13 pages
- publisher
- Royal Society of Chemistry
- external identifiers
-
- scopus:85083042566
- pmid:32103214
- ISSN
- 1477-9226
- DOI
- 10.1039/c9dt04799a
- language
- English
- LU publication?
- yes
- id
- 8138d627-1595-42c7-bbb1-c46299cfbde4
- date added to LUP
- 2020-04-30 12:25:24
- date last changed
- 2024-07-24 17:39:59
@article{8138d627-1595-42c7-bbb1-c46299cfbde4, abstract = {{<p>Twenty clusters of the general formula [(μ-H)<sub>2</sub>Ru<sub>3</sub>(μ<sub>3</sub>-S)(CO)<sub>7</sub>(μ-P-P∗)] (P-P∗ = chiral diphosphine of the ferrocene-based Walphos or Josiphos families) have been synthesised and characterised. The clusters have been tested as catalysts for asymmetric hydrogenation of tiglic acid [trans-2-methyl-2-butenoic acid]. The observed enantioselectivities and conversion rates strongly support catalysis by intact Ru<sub>3</sub> clusters. A catalytic mechanism involving an active Ru<sub>3</sub> catalyst generated by CO loss from [(μ-H)<sub>2</sub>Ru<sub>3</sub>(μ<sub>3</sub>-S)(CO)<sub>7</sub>(μ-P-P∗)] has been investigated by DFT calculations.</p>}}, author = {{Abdel-Magied, Ahmed F. and Theibich, Yusuf and Singh, Amrendra K. and Rahaman, Ahibur and Doverbratt, Isa and Raha, Arun K. and Haukka, Matti and Richmond, Michael G. and Nordlander, Ebbe}}, issn = {{1477-9226}}, language = {{eng}}, number = {{14}}, pages = {{4244--4256}}, publisher = {{Royal Society of Chemistry}}, series = {{Dalton Transactions}}, title = {{Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl clusters-diastereomeric control of enantioselectivity}}, url = {{http://dx.doi.org/10.1039/c9dt04799a}}, doi = {{10.1039/c9dt04799a}}, volume = {{49}}, year = {{2020}}, }