A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.
(2016) In Clinical Biochemistry 49(6). p.511-513- Abstract
- In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective of this study was to determine the cause of the increased %CDT levels.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8505155
- author
- Grahn, Ammi ; Bengtson, Per LU ; Eklund, Erik and Asin-Cayuela, Jorge
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Biochemistry
- volume
- 49
- issue
- 6
- pages
- 511 - 513
- publisher
- Elsevier
- external identifiers
-
- pmid:26656560
- scopus:84951088635
- wos:000373209700018
- pmid:26656560
- ISSN
- 1873-2933
- DOI
- 10.1016/j.clinbiochem.2015.12.001
- language
- English
- LU publication?
- yes
- id
- d77e3881-9546-4419-9fb5-69ae32706542 (old id 8505155)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26656560?dopt=Abstract
- date added to LUP
- 2016-04-04 08:16:25
- date last changed
- 2022-01-29 03:16:01
@article{d77e3881-9546-4419-9fb5-69ae32706542, abstract = {{In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective of this study was to determine the cause of the increased %CDT levels.}}, author = {{Grahn, Ammi and Bengtson, Per and Eklund, Erik and Asin-Cayuela, Jorge}}, issn = {{1873-2933}}, language = {{eng}}, number = {{6}}, pages = {{511--513}}, publisher = {{Elsevier}}, series = {{Clinical Biochemistry}}, title = {{A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.}}, url = {{http://dx.doi.org/10.1016/j.clinbiochem.2015.12.001}}, doi = {{10.1016/j.clinbiochem.2015.12.001}}, volume = {{49}}, year = {{2016}}, }