Electrophysiological evaluation of fleck retina and temporal macular thinning in X-Linked alport's syndrome
Al Akeely, Adel ; Schatz, Patrik LU
and Alhazimi, Amro
(2021)
In Middle East African Journal of Ophthalmology
28(4).
p.257-259
- Abstract
We report a 39-year-old with Alport's syndrome. The patient presented with anterior lenticonus, cataract, and a corrected distance visual acuity of 20/25 and 20/60 in the right and left eyes, respectively. Fundus examination revealed generalized retinal flecks sparing the fovea in both eyes. Optical coherence topography showed temporal macular thinning. Normal fundus autofluorescence was observed in both eyes. Full-field electroretinography (ERG) demonstrated normal photopic and scotopic responses, while multifocal ERG showed no reduction of amplitudes generated from the temporal thinned macula, compared to the nasal macula, indicating preserved functional integrity of the retina.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/88599029-d4f7-403f-b476-6f5b27484bc6
- author
- Al Akeely, Adel
; Schatz, Patrik
LU
and Alhazimi, Amro
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Alport's syndrome, COL4A5, fleck retina, full field electroretinography, multifocal electroretinography
- in
- Middle East African Journal of Ophthalmology
- volume
- 28
- issue
- 4
- pages
- 3 pages
- publisher
- Wolters Kluwer
- external identifiers
-
- scopus:85130166920
- pmid:35719281
- ISSN
- 0974-9233
- DOI
- 10.4103/meajo.meajo_7_21
- language
- English
- LU publication?
- yes
- id
- 88599029-d4f7-403f-b476-6f5b27484bc6
- date added to LUP
- 2022-07-08 15:14:55
- date last changed
- 2025-04-04 14:21:13
@article{88599029-d4f7-403f-b476-6f5b27484bc6,
abstract = {{<p>We report a 39-year-old with Alport's syndrome. The patient presented with anterior lenticonus, cataract, and a corrected distance visual acuity of 20/25 and 20/60 in the right and left eyes, respectively. Fundus examination revealed generalized retinal flecks sparing the fovea in both eyes. Optical coherence topography showed temporal macular thinning. Normal fundus autofluorescence was observed in both eyes. Full-field electroretinography (ERG) demonstrated normal photopic and scotopic responses, while multifocal ERG showed no reduction of amplitudes generated from the temporal thinned macula, compared to the nasal macula, indicating preserved functional integrity of the retina. </p>}},
author = {{Al Akeely, Adel and Schatz, Patrik and Alhazimi, Amro}},
issn = {{0974-9233}},
keywords = {{Alport's syndrome; COL4A5; fleck retina; full field electroretinography; multifocal electroretinography}},
language = {{eng}},
number = {{4}},
pages = {{257--259}},
publisher = {{Wolters Kluwer}},
series = {{Middle East African Journal of Ophthalmology}},
title = {{Electrophysiological evaluation of fleck retina and temporal macular thinning in X-Linked alport's syndrome}},
url = {{http://dx.doi.org/10.4103/meajo.meajo_7_21}},
doi = {{10.4103/meajo.meajo_7_21}},
volume = {{28}},
year = {{2021}},
}