Asymptomatic atherosclerosis and myocardial infarction: Risk modified by ability to adapt to stressful situations. Results from prospective cohort study "Men born in 1914", Malmo, Sweden
(2004) In Medical Science Monitor 10(10). p.549-556- Abstract
- Background: The purpose of this study was to investigate whether different behaviors in a stressful situation modify the risk of atherosclerosis in association with a myocardial infarction, cardiovascular mortality, and all-cause mortality. Many individuals have atherosclerotic changes in their arteries but may never experience any symptoms nor develop cardiovascular disease. A myocardial infarction is caused by a disruption of a vulnerable atherosclerotic plaque. The mechanisms that trigger these events are not fully understood, but among the proposed agents is psychological stress. A differential in risk exposure could be expected since individuals differ in their ability to cope with stressful situations. Materials/Methods: In the... (More)
- Background: The purpose of this study was to investigate whether different behaviors in a stressful situation modify the risk of atherosclerosis in association with a myocardial infarction, cardiovascular mortality, and all-cause mortality. Many individuals have atherosclerotic changes in their arteries but may never experience any symptoms nor develop cardiovascular disease. A myocardial infarction is caused by a disruption of a vulnerable atherosclerotic plaque. The mechanisms that trigger these events are not fully understood, but among the proposed agents is psychological stress. A differential in risk exposure could be expected since individuals differ in their ability to cope with stressful situations. Materials/Methods: In the prospective cohort study "Men born in 1914", atherosclerosis was noninvasively studied in the peripheral, carotid, and coronary arteries at a baseline examination in 1982/83. The serial Color Word Test, which is a semi-experimental way to assess how individuals adapt in a stressful situation, was administered at the same examination. Participants were followed-up regarding incidence of myocardial infarction and mortality until December 31 1996. Results: Atherosclerosis was associated with an increased risk of myocardial infarction (relative risk (RR) 2.96; 95% confidence interval (CI) 1.52 to 5.74) and cardiovascular mortality (RR 3.31; 95% Cl 2.08 to 5.28) during follow-up only among the men who showed maladaptive behavior. No excess risk could be established in men with an adaptive behavior pattern. Conclusions: The serial Color Word Test can assist in identifying men at high cardiovascular risk (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/897989
- author
- André-Petersson, Lena LU ; Hedblad, Bo LU ; Janzon, Lars LU and Steen, G
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- atherosclerosis, adaptive behavior, stress, noninvasive detection, Color Word Test
- in
- Medical Science Monitor
- volume
- 10
- issue
- 10
- pages
- 549 - 556
- publisher
- International Scientific Information (ISI)
- external identifiers
-
- wos:000224834000007
- pmid:15448593
- scopus:7044227598
- ISSN
- 1643-3750
- language
- English
- LU publication?
- yes
- id
- 8f07f749-bc75-4336-8129-a155f0fe2bec (old id 897989)
- alternative location
- http://www.medscimonit.com/abstracted.php?level=5&icid=11781
- date added to LUP
- 2016-04-01 12:32:51
- date last changed
- 2023-04-05 16:26:56
@article{8f07f749-bc75-4336-8129-a155f0fe2bec,
abstract = {{Background: The purpose of this study was to investigate whether different behaviors in a stressful situation modify the risk of atherosclerosis in association with a myocardial infarction, cardiovascular mortality, and all-cause mortality. Many individuals have atherosclerotic changes in their arteries but may never experience any symptoms nor develop cardiovascular disease. A myocardial infarction is caused by a disruption of a vulnerable atherosclerotic plaque. The mechanisms that trigger these events are not fully understood, but among the proposed agents is psychological stress. A differential in risk exposure could be expected since individuals differ in their ability to cope with stressful situations. Materials/Methods: In the prospective cohort study "Men born in 1914", atherosclerosis was noninvasively studied in the peripheral, carotid, and coronary arteries at a baseline examination in 1982/83. The serial Color Word Test, which is a semi-experimental way to assess how individuals adapt in a stressful situation, was administered at the same examination. Participants were followed-up regarding incidence of myocardial infarction and mortality until December 31 1996. Results: Atherosclerosis was associated with an increased risk of myocardial infarction (relative risk (RR) 2.96; 95% confidence interval (CI) 1.52 to 5.74) and cardiovascular mortality (RR 3.31; 95% Cl 2.08 to 5.28) during follow-up only among the men who showed maladaptive behavior. No excess risk could be established in men with an adaptive behavior pattern. Conclusions: The serial Color Word Test can assist in identifying men at high cardiovascular risk}},
author = {{André-Petersson, Lena and Hedblad, Bo and Janzon, Lars and Steen, G}},
issn = {{1643-3750}},
keywords = {{atherosclerosis; adaptive behavior; stress; noninvasive detection; Color Word Test}},
language = {{eng}},
number = {{10}},
pages = {{549--556}},
publisher = {{International Scientific Information (ISI)}},
series = {{Medical Science Monitor}},
title = {{Asymptomatic atherosclerosis and myocardial infarction: Risk modified by ability to adapt to stressful situations. Results from prospective cohort study "Men born in 1914", Malmo, Sweden}},
url = {{http://www.medscimonit.com/abstracted.php?level=5&icid=11781}},
volume = {{10}},
year = {{2004}},
}