Photoallergic contact dermatitis from ketoprofen induced by drug-contaminated personal objects
(2004) In Journal of American Academy of Dermatology 50(2). p.215-219- Abstract
- Background: Photoallergic contact dermatitis from ketoprofen has been recognized since the mid-1980s. Skin reactions have been reported to continue weeks after discontinuation of ketoprofen. One reason for this could be residual ketoprofen in the skin, which has been shown in a skin biopsy specimen. Objective: We sought to report on 3 cases of photoallergic contact dermatitis from ketoprofen in topical anti-inflammatory gels and on relapses of dermatitis appearing after use of ketoprofen-contaminated objects. Methods: We patch and photopatch tested, with standard series, the anti-inflammatory gel, ketoprofen, and its ingredients in serial dilutions and extracts of personal objects. We performed chemical investigations of personal objects... (More)
- Background: Photoallergic contact dermatitis from ketoprofen has been recognized since the mid-1980s. Skin reactions have been reported to continue weeks after discontinuation of ketoprofen. One reason for this could be residual ketoprofen in the skin, which has been shown in a skin biopsy specimen. Objective: We sought to report on 3 cases of photoallergic contact dermatitis from ketoprofen in topical anti-inflammatory gels and on relapses of dermatitis appearing after use of ketoprofen-contaminated objects. Methods: We patch and photopatch tested, with standard series, the anti-inflammatory gel, ketoprofen, and its ingredients in serial dilutions and extracts of personal objects. We performed chemical investigations of personal objects with thin-layer chromatography, high-pressure liquid chromatography, and gas chromatography-mass spectrometry. Results: Photoallergy was demonstrated to ketoprofen, which was detected in personal objects. Conclusion: Relapses of photoallergic contact dermatitis in patients photoallergic to ketoprofen can be induced by ketoprofen-contaminated objects such as bandages and slippers. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/899404
- author
- Hindsén, Monica LU ; Isaksson, Marléne LU ; Persson, L ; Zimersson, E and Bruze, Magnus LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of American Academy of Dermatology
- volume
- 50
- issue
- 2
- pages
- 215 - 219
- publisher
- Elsevier
- external identifiers
-
- wos:000188710100007
- scopus:0842310851
- ISSN
- 0190-9622
- DOI
- 10.1016/j.jaad.2003.07.007
- language
- English
- LU publication?
- yes
- id
- c0b2c840-1960-452c-9111-1869f88857b5 (old id 899404)
- date added to LUP
- 2016-04-01 12:10:46
- date last changed
- 2022-02-03 18:39:32
@article{c0b2c840-1960-452c-9111-1869f88857b5, abstract = {{Background: Photoallergic contact dermatitis from ketoprofen has been recognized since the mid-1980s. Skin reactions have been reported to continue weeks after discontinuation of ketoprofen. One reason for this could be residual ketoprofen in the skin, which has been shown in a skin biopsy specimen. Objective: We sought to report on 3 cases of photoallergic contact dermatitis from ketoprofen in topical anti-inflammatory gels and on relapses of dermatitis appearing after use of ketoprofen-contaminated objects. Methods: We patch and photopatch tested, with standard series, the anti-inflammatory gel, ketoprofen, and its ingredients in serial dilutions and extracts of personal objects. We performed chemical investigations of personal objects with thin-layer chromatography, high-pressure liquid chromatography, and gas chromatography-mass spectrometry. Results: Photoallergy was demonstrated to ketoprofen, which was detected in personal objects. Conclusion: Relapses of photoallergic contact dermatitis in patients photoallergic to ketoprofen can be induced by ketoprofen-contaminated objects such as bandages and slippers.}}, author = {{Hindsén, Monica and Isaksson, Marléne and Persson, L and Zimersson, E and Bruze, Magnus}}, issn = {{0190-9622}}, language = {{eng}}, number = {{2}}, pages = {{215--219}}, publisher = {{Elsevier}}, series = {{Journal of American Academy of Dermatology}}, title = {{Photoallergic contact dermatitis from ketoprofen induced by drug-contaminated personal objects}}, url = {{http://dx.doi.org/10.1016/j.jaad.2003.07.007}}, doi = {{10.1016/j.jaad.2003.07.007}}, volume = {{50}}, year = {{2004}}, }