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The ethics of synthetic DNA

Villalba, Adrian ; Smajdor, Anna ; Brassington, Iain and Cutas, Daniela LU (2024) In Journal of Medical Ethics
Abstract
In this paper, we discuss the ethical concerns that may arise from the synthesis of human DNA. To date, only small stretches of DNA have been constructed, but the prospect of generating human genomes is becoming feasible. At the same time, the significance of genes for identity, health and reproduction is coming under increased scrutiny. We examine the implications of DNA synthesis and its impact on debates over the relationship with our DNA and the ownership of our genes, its potential to disrupt common understandings of reproduction and privacy, and the way in which synthetic DNA challenges traditional associations between genes and identity. We explore the degree to which synthetic DNA may further undermine overgeneticised accounts of... (More)
In this paper, we discuss the ethical concerns that may arise from the synthesis of human DNA. To date, only small stretches of DNA have been constructed, but the prospect of generating human genomes is becoming feasible. At the same time, the significance of genes for identity, health and reproduction is coming under increased scrutiny. We examine the implications of DNA synthesis and its impact on debates over the relationship with our DNA and the ownership of our genes, its potential to disrupt common understandings of reproduction and privacy, and the way in which synthetic DNA challenges traditional associations between genes and identity. We explore the degree to which synthetic DNA may further undermine overgeneticised accounts of identity, health, reproduction, parenthood and privacy that are prevalent in the public domain and in some areas of policy-making. While avoiding making normative claims of our own, we conclude that there is a need for reflection on the ethical implications of these developing technologies before they are on us. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
synthetic DNA, identity, privacy, reproduction, reproductive ethics
in
Journal of Medical Ethics
publisher
BMJ Publishing Group
external identifiers
  • pmid:39567177
  • scopus:85214653120
ISSN
1473-4257
DOI
10.1136/jme-2024-110124
language
English
LU publication?
yes
id
8e801006-a697-4c01-966b-4c751d1f99e0
date added to LUP
2024-11-21 10:19:06
date last changed
2025-04-04 14:51:28
@article{8e801006-a697-4c01-966b-4c751d1f99e0,
  abstract     = {{In this paper, we discuss the ethical concerns that may arise from the synthesis of human DNA. To date, only small stretches of DNA have been constructed, but the prospect of generating human genomes is becoming feasible. At the same time, the significance of genes for identity, health and reproduction is coming under increased scrutiny. We examine the implications of DNA synthesis and its impact on debates over the relationship with our DNA and the ownership of our genes, its potential to disrupt common understandings of reproduction and privacy, and the way in which synthetic DNA challenges traditional associations between genes and identity. We explore the degree to which synthetic DNA may further undermine overgeneticised accounts of identity, health, reproduction, parenthood and privacy that are prevalent in the public domain and in some areas of policy-making. While avoiding making normative claims of our own, we conclude that there is a need for reflection on the ethical implications of these developing technologies before they are on us.}},
  author       = {{Villalba, Adrian and Smajdor, Anna and Brassington, Iain and Cutas, Daniela}},
  issn         = {{1473-4257}},
  keywords     = {{synthetic DNA; identity; privacy; reproduction; reproductive ethics}},
  language     = {{eng}},
  month        = {{11}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{Journal of Medical Ethics}},
  title        = {{The ethics of synthetic DNA}},
  url          = {{http://dx.doi.org/10.1136/jme-2024-110124}},
  doi          = {{10.1136/jme-2024-110124}},
  year         = {{2024}},
}