Robustness of metabolic maps
Ahrén, Dag LU
and Ouzounis, Christos
(2004)
In Journal of Bioinformatics and Computational Biology
2(3).
p.589-593
- Abstract
- With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on... (More)
- With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/952546
- author
- Ahrén, Dag
LU
and Ouzounis, Christos
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Metabolic reconstructionmetabolic mapsgenome analysisrobustness analysisbiochemical pathways
- in
- Journal of Bioinformatics and Computational Biology
- volume
- 2
- issue
- 3
- pages
- 589 - 593
- publisher
- World Scientific Publishing
- external identifiers
-
- scopus:4644254273
- ISSN
- 0219-7200
- DOI
- 10.1142/S021972000400079X
- language
- English
- LU publication?
- no
- id
- b6fe1295-133e-4c28-a53d-7154df37c088 (old id 952546)
- date added to LUP
- 2016-04-01 12:36:56
- date last changed
- 2024-01-09 02:47:48
@article{b6fe1295-133e-4c28-a53d-7154df37c088,
abstract = {{With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data.}},
author = {{Ahrén, Dag and Ouzounis, Christos}},
issn = {{0219-7200}},
keywords = {{Metabolic reconstructionmetabolic mapsgenome analysisrobustness analysisbiochemical pathways}},
language = {{eng}},
number = {{3}},
pages = {{589--593}},
publisher = {{World Scientific Publishing}},
series = {{Journal of Bioinformatics and Computational Biology}},
title = {{Robustness of metabolic maps}},
url = {{http://dx.doi.org/10.1142/S021972000400079X}},
doi = {{10.1142/S021972000400079X}},
volume = {{2}},
year = {{2004}},
}