Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Treatment outcome and factors affecting time to recovery in children with severe acute malnutrition treated at outpatient therapeutic care program

Merid Mengesha, Melkamu LU orcid ; Deyessa, Nigussie ; Tegegne, Balewgizie Sileshi and Dessie, Yadeta (2016) In Global Health Action 9(1).
Abstract
Background
The outpatient therapeutic care program (OTP) of children with severe acute malnutrition (SAM) has been decentralized to health post level in Ethiopia since 2008–2009. However, there is a lack of evidence regarding treatment outcomes and factors related to the duration of stay on treatment after its decentralization to health post level.
Objective
This study was aimed to assess treatment outcome and factors affecting time to recovery in children with SAM treated at OTP.
Design
Health facility–based retrospective cohort study was conducted using data from 348 patient cards. The outcome variable was time to recovery. Descriptive analysis was done using percentages for categorical data and mean/median for... (More)
Background
The outpatient therapeutic care program (OTP) of children with severe acute malnutrition (SAM) has been decentralized to health post level in Ethiopia since 2008–2009. However, there is a lack of evidence regarding treatment outcomes and factors related to the duration of stay on treatment after its decentralization to health post level.
Objective
This study was aimed to assess treatment outcome and factors affecting time to recovery in children with SAM treated at OTP.
Design
Health facility–based retrospective cohort study was conducted using data from 348 patient cards. The outcome variable was time to recovery. Descriptive analysis was done using percentages for categorical data and mean/median for continuous variables. A robust method of analyzing time to event data, the Cox proportional-hazard regression, was used. All statistical tests in this study are declared significant at pResult
89.1% of children with kwashiorkor and 69.4% of children with marasmus were recovered. Of the total children studied, 22% were readmitted cases. The median time of recovery was 35 days for children with kwashiorkor and 49 days for children with marasmus. Children older than 3 years were 33% less likely to achieve nutritional recovery [adjusted hazard ratio, AHR=0.67, 95% confidence interval, CI (0.46, 0.97)].
Similarly, marasmic children stayed longer on treatment [AHR=0.42, 95% CI (0.32, 0.56)]. However, children who gained Mid-Upper Arm Circumference (MUAC) ≥ 0.24 mm/day were 59% more likely to recover faster [AHR=1.59, 95% CI (1.23, 2.06)].
Conclusions
Close monitoring of weight and MUAC gain to assess nutritional improvement with due emphasis given to children with lower admission weight, children of age 3 years and above and marasmic children will have a positive effect on treatment duration and outcome. (Less)
Please use this url to cite or link to this publication:
author
; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Global Health Action
volume
9
issue
1
publisher
Co-Action Publishing
external identifiers
  • scopus:84989340824
ISSN
1654-9716
DOI
10.3402/gha.v9.30704
language
English
LU publication?
no
id
970f3667-7adf-4dd8-81a6-ab131e2bb433
date added to LUP
2023-06-04 21:45:28
date last changed
2024-03-26 09:28:11
@article{970f3667-7adf-4dd8-81a6-ab131e2bb433,
  abstract     = {{Background<br/>The outpatient therapeutic care program (OTP) of children with severe acute malnutrition (SAM) has been decentralized to health post level in Ethiopia since 2008–2009. However, there is a lack of evidence regarding treatment outcomes and factors related to the duration of stay on treatment after its decentralization to health post level.<br/>Objective<br/>This study was aimed to assess treatment outcome and factors affecting time to recovery in children with SAM treated at OTP.<br/>Design<br/>Health facility–based retrospective cohort study was conducted using data from 348 patient cards. The outcome variable was time to recovery. Descriptive analysis was done using percentages for categorical data and mean/median for continuous variables. A robust method of analyzing time to event data, the Cox proportional-hazard regression, was used. All statistical tests in this study are declared significant at pResult<br/>89.1% of children with kwashiorkor and 69.4% of children with marasmus were recovered. Of the total children studied, 22% were readmitted cases. The median time of recovery was 35 days for children with kwashiorkor and 49 days for children with marasmus. Children older than 3 years were 33% less likely to achieve nutritional recovery [adjusted hazard ratio, AHR=0.67, 95% confidence interval, CI (0.46, 0.97)]. <br/>Similarly, marasmic children stayed longer on treatment [AHR=0.42, 95% CI (0.32, 0.56)]. However, children who gained Mid-Upper Arm Circumference (MUAC) ≥ 0.24 mm/day were 59% more likely to recover faster [AHR=1.59, 95% CI (1.23, 2.06)].<br/>Conclusions<br/>Close monitoring of weight and MUAC gain to assess nutritional improvement with due emphasis given to children with lower admission weight, children of age 3 years and above and marasmic children will have a positive effect on treatment duration and outcome.}},
  author       = {{Merid Mengesha, Melkamu and Deyessa, Nigussie and Tegegne, Balewgizie Sileshi and Dessie, Yadeta}},
  issn         = {{1654-9716}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{1}},
  publisher    = {{Co-Action Publishing}},
  series       = {{Global Health Action}},
  title        = {{Treatment outcome and factors affecting time to recovery in children with severe acute malnutrition treated at outpatient therapeutic care program}},
  url          = {{http://dx.doi.org/10.3402/gha.v9.30704}},
  doi          = {{10.3402/gha.v9.30704}},
  volume       = {{9}},
  year         = {{2016}},
}