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Analogues of 1D-Myo-inositol 1,2,6-trisphosphate. Preparation of carboxymethyl and 2-hydroxyethyl phosphate derivatives

Malmberg, Mats and Rehnberg, Nicola LU orcid (1997) In Journal of Carbohydrate Chemistry 16(1). p.109-112
Abstract

Acylation of 1D-myo-inositol 1,2,6-trisphosphate (α-trinositol) followed by alkylation of the phosphate groups with benzyl bromoacetate or 2-benzyloxyethyl iodide and deprotection provides a route to analogues with modified phosphate groups. The modifications made alter steric and ionisation properties but the possibility to participate in hydrogen bonding and ionic interaction is retained.

Please use this url to cite or link to this publication:
author
and
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Carbohydrate Chemistry
volume
16
issue
1
pages
4 pages
publisher
Marcel Dekker
external identifiers
  • scopus:0031541164
ISSN
0732-8303
DOI
10.1080/07328309708006513
language
English
LU publication?
no
id
9c449268-15ca-492c-9913-c71853f55e9c
date added to LUP
2021-11-11 12:50:02
date last changed
2022-02-02 01:16:14
@article{9c449268-15ca-492c-9913-c71853f55e9c,
  abstract     = {{<p>Acylation of 1D-<i>myo</i>-inositol 1,2,6-trisphosphate (α-trinositol) followed by alkylation of the phosphate groups with benzyl bromoacetate or 2-benzyloxyethyl iodide and deprotection provides a route to analogues with modified phosphate groups. The modifications made alter steric and ionisation properties but the possibility to participate in hydrogen bonding and ionic interaction is retained.</p>}},
  author       = {{Malmberg, Mats and Rehnberg, Nicola}},
  issn         = {{0732-8303}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{109--112}},
  publisher    = {{Marcel Dekker}},
  series       = {{Journal of Carbohydrate Chemistry}},
  title        = {{Analogues of 1D-<i>Myo</i>-inositol 1,2,6-trisphosphate. Preparation of carboxymethyl and 2-hydroxyethyl phosphate derivatives}},
  url          = {{http://dx.doi.org/10.1080/07328309708006513}},
  doi          = {{10.1080/07328309708006513}},
  volume       = {{16}},
  year         = {{1997}},
}