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An Integrated Thermal Sensor Array For Multianalyte determination demonstrated With Glucose, Urea And Penicillin

Xie, Bin LU and Danielsson, Bengt LU (1995) 1. p.501-503
Abstract
An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains ten thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technologies. This sensor allows to determine maximum five different analytes nearly simultaneously by serially dividing the single microchannel into five distinct detection regions. Each of the regions contains one immobilized enzyme and a pair of thermistors for differential measurement of the thermal signal corresponding to the enzyme reaction. Using this device, glucose, urea and penicillin mixed samples at different concentrations were determined. The linear ranges of at least 25 mM for... (More)
An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains ten thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technologies. This sensor allows to determine maximum five different analytes nearly simultaneously by serially dividing the single microchannel into five distinct detection regions. Each of the regions contains one immobilized enzyme and a pair of thermistors for differential measurement of the thermal signal corresponding to the enzyme reaction. Using this device, glucose, urea and penicillin mixed samples at different concentrations were determined. The linear ranges of at least 25 mM for urea and penicillin, and up to 20 mM for glucose were obtained using a sample volume of 20 μ/l. (Less)
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Proceedings of the International Solid-State Sensors and Actuators Conference - TRANSDUCERS '95
volume
1
pages
3 pages
publisher
IEEE Press
external identifiers
  • scopus:0029512003
ISBN
91-630-3473-5
DOI
10.1109/SENSOR.1995.717264
language
English
LU publication?
yes
id
a41ee692-8947-4375-9502-6c4cf9c0763c
date added to LUP
2021-10-27 19:35:15
date last changed
2021-11-01 14:26:47
@inproceedings{a41ee692-8947-4375-9502-6c4cf9c0763c,
  abstract     = {{An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains ten thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technologies. This sensor allows to determine maximum five different analytes nearly simultaneously by serially dividing the single microchannel into five distinct detection regions. Each of the regions contains one immobilized enzyme and a pair of thermistors for differential measurement of the thermal signal corresponding to the enzyme reaction. Using this device, glucose, urea and penicillin mixed samples at different concentrations were determined. The linear ranges of at least 25 mM for urea and penicillin, and up to 20 mM for glucose were obtained using a sample volume of 20 μ/l.}},
  author       = {{Xie, Bin and Danielsson, Bengt}},
  booktitle    = {{Proceedings of the International Solid-State Sensors and Actuators Conference - TRANSDUCERS '95}},
  isbn         = {{91-630-3473-5}},
  language     = {{eng}},
  pages        = {{501--503}},
  publisher    = {{IEEE Press}},
  title        = {{An Integrated Thermal Sensor Array For Multianalyte determination demonstrated With Glucose, Urea And Penicillin}},
  url          = {{http://dx.doi.org/10.1109/SENSOR.1995.717264}},
  doi          = {{10.1109/SENSOR.1995.717264}},
  volume       = {{1}},
  year         = {{1995}},
}