The effect of sociodemographic factors, parity and cervical cancer on antibiotic treatment for uncomplicated cystitis in women : A nationwide cohort study
(2021) In Antibiotics 10(11).- Abstract
Background: Uncomplicated cystitis is one of the most common reasons for antibiotic treatment in otherwise healthy women. Nationwide studies on antibiotic treatment for this infection and in relation to factors beyond the infection itself have hitherto not been available. Methods: This was a nationwide open cohort study consisting of 352,507 women aged 15–50 years with uncomplicated cystitis (2006–2018). The outcome was a redeemed antibiotic prescription within five days from the cystitis diagnosis. Logistic regression models were used to examine the relationship between the outcome and the predictor variables. Results: This study identified 192,065 redeemed treatments (54.5%). Several sociodemographic variables were associated with... (More)
Background: Uncomplicated cystitis is one of the most common reasons for antibiotic treatment in otherwise healthy women. Nationwide studies on antibiotic treatment for this infection and in relation to factors beyond the infection itself have hitherto not been available. Methods: This was a nationwide open cohort study consisting of 352,507 women aged 15–50 years with uncomplicated cystitis (2006–2018). The outcome was a redeemed antibiotic prescription within five days from the cystitis diagnosis. Logistic regression models were used to examine the relationship between the outcome and the predictor variables. Results: This study identified 192,065 redeemed treatments (54.5%). Several sociodemographic variables were associated with antibiotic treatment. For example, women with the lowest income had an odds ratio (OR) of 1.26 (95% CI 1.23–1.28) compared to those with the highest income. History of cervical cancer and high parity were also associated with lower treatment rates. Conclusion: This study presents novel factors beyond the infection which seem to affect the antibiotic treatment for uncomplicated cystitis in women. Future studies to investigate possible mechanisms are warranted in order to properly use our findings. This may help healthcare workers and planners to provide a more equal treatment plan for this common infection, which may reduce misuse of antibiotics, decrease costs and improve efforts against antibiotic resistance.
(Less)
- author
- Jansåker, Filip LU ; Li, Xinjun LU ; Knudsen, Jenny Dahl ; Nymberg, Veronica Milos LU and Sundquist, Kristina LU
- organization
- publishing date
- 2021-11
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Antibiotics, Cervical cancer, Cystitis, Parity, Sociodemographic factors, UTI
- in
- Antibiotics
- volume
- 10
- issue
- 11
- article number
- 1389
- publisher
- MDPI AG
- external identifiers
-
- pmid:34827326
- scopus:85119613210
- ISSN
- 2079-6382
- DOI
- 10.3390/antibiotics10111389
- language
- English
- LU publication?
- yes
- id
- b5e36d11-cea4-452a-948d-b36f8ba2d4a1
- date added to LUP
- 2021-12-03 14:11:22
- date last changed
- 2024-06-15 22:05:51
@article{b5e36d11-cea4-452a-948d-b36f8ba2d4a1,
abstract = {{<p>Background: Uncomplicated cystitis is one of the most common reasons for antibiotic treatment in otherwise healthy women. Nationwide studies on antibiotic treatment for this infection and in relation to factors beyond the infection itself have hitherto not been available. Methods: This was a nationwide open cohort study consisting of 352,507 women aged 15–50 years with uncomplicated cystitis (2006–2018). The outcome was a redeemed antibiotic prescription within five days from the cystitis diagnosis. Logistic regression models were used to examine the relationship between the outcome and the predictor variables. Results: This study identified 192,065 redeemed treatments (54.5%). Several sociodemographic variables were associated with antibiotic treatment. For example, women with the lowest income had an odds ratio (OR) of 1.26 (95% CI 1.23–1.28) compared to those with the highest income. History of cervical cancer and high parity were also associated with lower treatment rates. Conclusion: This study presents novel factors beyond the infection which seem to affect the antibiotic treatment for uncomplicated cystitis in women. Future studies to investigate possible mechanisms are warranted in order to properly use our findings. This may help healthcare workers and planners to provide a more equal treatment plan for this common infection, which may reduce misuse of antibiotics, decrease costs and improve efforts against antibiotic resistance.</p>}},
author = {{Jansåker, Filip and Li, Xinjun and Knudsen, Jenny Dahl and Nymberg, Veronica Milos and Sundquist, Kristina}},
issn = {{2079-6382}},
keywords = {{Antibiotics; Cervical cancer; Cystitis; Parity; Sociodemographic factors; UTI}},
language = {{eng}},
number = {{11}},
publisher = {{MDPI AG}},
series = {{Antibiotics}},
title = {{The effect of sociodemographic factors, parity and cervical cancer on antibiotic treatment for uncomplicated cystitis in women : A nationwide cohort study}},
url = {{http://dx.doi.org/10.3390/antibiotics10111389}},
doi = {{10.3390/antibiotics10111389}},
volume = {{10}},
year = {{2021}},
}