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Konsequenzen aus intrauterin erkannter plazentarer Versorgungsstörung

Maršál, Karel LU and Vetter, Klaus (2020) In Gynakologe 53.
Abstract

The intrauterine milieu can have an impact on an individualʼs entire life. Restricted supply not only causes reduced growth, but also irreparable damage, e.g., cardiovascular or neurocognitive. Issues to be addressed by prenatal medicine include not only possible therapeutic aspects, but also the question of the optimal medical strategy, which aims to minimize damage from undersupply on the one hand and from premature birth on the other. In addition to increased perinatal mortality and morbidity, intrauterine growth restriction (IUGR) fetuses with abnormal Doppler findings in the umbilical artery show suboptimal postnatal neurological, intellectual, and vascular development. An active approach by the entire perinatological team,... (More)

The intrauterine milieu can have an impact on an individualʼs entire life. Restricted supply not only causes reduced growth, but also irreparable damage, e.g., cardiovascular or neurocognitive. Issues to be addressed by prenatal medicine include not only possible therapeutic aspects, but also the question of the optimal medical strategy, which aims to minimize damage from undersupply on the one hand and from premature birth on the other. In addition to increased perinatal mortality and morbidity, intrauterine growth restriction (IUGR) fetuses with abnormal Doppler findings in the umbilical artery show suboptimal postnatal neurological, intellectual, and vascular development. An active approach by the entire perinatological team, regardless of gestational age, can help to improve results in the case of absent or reversed end-diastolic (ARED) flow in the umbilical arteries—even in extremely premature situations—before the appearance of a pathological cardiotocogram (CTG) or changes in ductus venosus blood flow. For a good result, it is beneficial to ensure that disadvantages arising despite timely interventions are recognized as early as possible to limit their negative effects after birth and later in life. In the case of pathological findings, an obstetric approach with the sole aim of producing a surviving child is no longer an option.

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Please use this url to cite or link to this publication:
author
and
organization
alternative title
Consequences of intrauterine-detected placental supply disorder
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Doppler Ultrasonography, Perinatal morbidity, Placental insufficiency, Pro-active management, Umbilical arteries
in
Gynakologe
volume
53
article number
444–454
publisher
Springer
external identifiers
  • scopus:85086700288
ISSN
0017-5994
DOI
10.1007/s00129-020-04624-0
language
German
LU publication?
yes
id
b7098909-2909-4afb-8680-d036fc54fdf6
date added to LUP
2020-07-13 11:00:37
date last changed
2022-04-18 23:36:18
@article{b7098909-2909-4afb-8680-d036fc54fdf6,
  abstract     = {{<p>The intrauterine milieu can have an impact on an individualʼs entire life. Restricted supply not only causes reduced growth, but also irreparable damage, e.g., cardiovascular or neurocognitive. Issues to be addressed by prenatal medicine include not only possible therapeutic aspects, but also the question of the optimal medical strategy, which aims to minimize damage from undersupply on the one hand and from premature birth on the other. In addition to increased perinatal mortality and morbidity, intrauterine growth restriction (IUGR) fetuses with abnormal Doppler findings in the umbilical artery show suboptimal postnatal neurological, intellectual, and vascular development. An active approach by the entire perinatological team, regardless of gestational age, can help to improve results in the case of absent or reversed end-diastolic (ARED) flow in the umbilical arteries—even in extremely premature situations—before the appearance of a pathological cardiotocogram (CTG) or changes in ductus venosus blood flow. For a good result, it is beneficial to ensure that disadvantages arising despite timely interventions are recognized as early as possible to limit their negative effects after birth and later in life. In the case of pathological findings, an obstetric approach with the sole aim of producing a surviving child is no longer an option.</p>}},
  author       = {{Maršál, Karel and Vetter, Klaus}},
  issn         = {{0017-5994}},
  keywords     = {{Doppler Ultrasonography; Perinatal morbidity; Placental insufficiency; Pro-active management; Umbilical arteries}},
  language     = {{ger}},
  publisher    = {{Springer}},
  series       = {{Gynakologe}},
  title        = {{Konsequenzen aus intrauterin erkannter plazentarer Versorgungsstörung}},
  url          = {{http://dx.doi.org/10.1007/s00129-020-04624-0}},
  doi          = {{10.1007/s00129-020-04624-0}},
  volume       = {{53}},
  year         = {{2020}},
}