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Distribution of cystatin C (gamma-trace), an inhibitor of lysosomal cysteine proteinases, in the anterior lobe of simian and human pituitary glands

Möller, C A ; Löfberg, H LU ; Grubb, A O LU orcid ; Olsson, S O ; Davies, M E and Barrett, A J (1985) In Neuroendocrinology 41(5). p.400-404
Abstract

Cystatin C, a protein inhibitor of lysosomal cysteine proteinases, was demonstrated by immunohistochemical techniques to be present in most luteinizing hormone- (LH-)containing cells in simian and human adenohypophyses. Immunoreactivity of cystatin C was also found in simian adrenocorticotrophic hormone- (ACTH-)containing cells localized to an area corresponding to the pars intermedia but not in the ACTH-containing cells of the anterior pituitary lobe of monkey. No immunoreactivity of cystatin C was detected in the growth hormone- (GH-) and prolactin-containing cells of monkey and man.

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organization
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Contribution to journal
publication status
published
subject
keywords
Adrenocorticotropic Hormone/metabolism, Aged, Animals, Chlorocebus aethiops, Cystatin C, Cystatins, Female, Growth Hormone/metabolism, Humans, Immunoenzyme Techniques, Luteinizing Hormone/metabolism, Male, Middle Aged, Pituitary Gland, Anterior/cytology, Prolactin/metabolism, Proteins/metabolism
in
Neuroendocrinology
volume
41
issue
5
pages
400 - 404
publisher
Karger
external identifiers
  • pmid:2997651
  • scopus:0022358434
ISSN
0028-3835
DOI
10.1159/000124209
language
English
LU publication?
yes
id
bf11bd34-c276-436e-aed3-1681c8cd198c
date added to LUP
2021-10-26 09:53:26
date last changed
2024-01-12 02:54:35
@article{bf11bd34-c276-436e-aed3-1681c8cd198c,
  abstract     = {{<p>Cystatin C, a protein inhibitor of lysosomal cysteine proteinases, was demonstrated by immunohistochemical techniques to be present in most luteinizing hormone- (LH-)containing cells in simian and human adenohypophyses. Immunoreactivity of cystatin C was also found in simian adrenocorticotrophic hormone- (ACTH-)containing cells localized to an area corresponding to the pars intermedia but not in the ACTH-containing cells of the anterior pituitary lobe of monkey. No immunoreactivity of cystatin C was detected in the growth hormone- (GH-) and prolactin-containing cells of monkey and man.</p>}},
  author       = {{Möller, C A and Löfberg, H and Grubb, A O and Olsson, S O and Davies, M E and Barrett, A J}},
  issn         = {{0028-3835}},
  keywords     = {{Adrenocorticotropic Hormone/metabolism; Aged; Animals; Chlorocebus aethiops; Cystatin C; Cystatins; Female; Growth Hormone/metabolism; Humans; Immunoenzyme Techniques; Luteinizing Hormone/metabolism; Male; Middle Aged; Pituitary Gland, Anterior/cytology; Prolactin/metabolism; Proteins/metabolism}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{400--404}},
  publisher    = {{Karger}},
  series       = {{Neuroendocrinology}},
  title        = {{Distribution of cystatin C (gamma-trace), an inhibitor of lysosomal cysteine proteinases, in the anterior lobe of simian and human pituitary glands}},
  url          = {{http://dx.doi.org/10.1159/000124209}},
  doi          = {{10.1159/000124209}},
  volume       = {{41}},
  year         = {{1985}},
}