Physicians’, pharmacists’, and nurses’ education of patients about antibiotic use and antimicrobial resistance in primary care settings: a qualitative systematic literature review
Balea, Lavinia Bianca ; Gulestø, Ragnhild Julante Andersen ; Xu, Hongxuan LU and Glasdam, Stinne LU
(2025)
In Frontiers in Antibiotics
3.
- Abstract
- Background: Patients’ adherence to antibiotic treatment and related prevention of AMR is significant. Understanding healthcare professionals’ strategies for advising and educating patients in primary care settings is crucial.
Aim: From the perspectives of professionals and patients, to explore how physicians, pharmacists, and nurses educate patients about antibiotic use and antimicrobial resistance in primary care settings.
Methods: A qualitative systematic literature review was conducted in MEDLINE, EMBASE, CINAHL Complete, Eric, SocINDEX, PsycInfo, Web of Science and Scopus. The study included 102 publications, followed PRISMA recommendations and was registered in PROSPERO (reg.no. CRD4202455761). The studies were... (More) - Background: Patients’ adherence to antibiotic treatment and related prevention of AMR is significant. Understanding healthcare professionals’ strategies for advising and educating patients in primary care settings is crucial.
Aim: From the perspectives of professionals and patients, to explore how physicians, pharmacists, and nurses educate patients about antibiotic use and antimicrobial resistance in primary care settings.
Methods: A qualitative systematic literature review was conducted in MEDLINE, EMBASE, CINAHL Complete, Eric, SocINDEX, PsycInfo, Web of Science and Scopus. The study included 102 publications, followed PRISMA recommendations and was registered in PROSPERO (reg.no. CRD4202455761). The studies were screened and selected based on specific inclusion and exclusion criteria using Covidence. Quality appraisal followed the Critical Appraisal Skills Program (CASP) qualitative study checklist. Data were extracted, and the analysis consisted of a descriptive numerical summary analysis and a qualitative thematic analysis.
Results: The analyzed studies spanned multiple countries and settings and included perspectives of primary care physicians, pharmacists, nurses and patients. Two main themes emerged: (1) Relationships between professionals and patients influenced educational strategies, showing that trust and rapport between healthcare professionals and patients played a crucial role in shaping educational strategies around antibiotic use; (2) The organizational structures challenged professionals in guiding and educating patients, highlighting how limited resources, time constraints, and system-level pressures hindered healthcare professionals’ ability to provide consistent and effective education. Often, structural challenges led to not educating the patients on the risks of antibiotic misuse and antimicrobial resistance. The use of delayed prescriptions emerged as a strategy for improved AMR stewardship and to meet patients’ expectations for antibiotic treatment, though it raised concerns about undermining professional responsibility and authority in ensuring appropriate antibiotic use.
Conclusion: Healthcare professionals’ role in educating patients about antibiotic use and AMR in primary care settings was complex, with different challenges faced by nurses, pharmacists and primary care physicians. These challenges extended beyond the clinical level, including relational, social and structural factors. Power dynamics, trust issues, and time pressures often hindered effective education on antibiotic use. Addressing gaps in education on antibiotic use and AMR requires acknowledging these multifaceted challenges, with future efforts focusing on better supporting healthcare professionals in this context.
Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD4202455761. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/c35444f0-989b-4dfd-8b58-44a98426aa8b
- author
- Balea, Lavinia Bianca
; Gulestø, Ragnhild Julante Andersen
; Xu, Hongxuan
LU
and Glasdam, Stinne
LU
- organization
- publishing date
- 2025-01-09
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- antimicrobial resistance, patient education, primary care, professionals, qualitative systematic literature review, pharmacists, physicians, general practitioners, nurses, AMR stewardship, antibiotics
- in
- Frontiers in Antibiotics
- volume
- 3
- article number
- 1507868
- publisher
- Frontiers Media S. A.
- external identifiers
-
- scopus:85216009943
- pmid:39850331
- ISSN
- 2813-2467
- DOI
- 10.3389/frabi.2024.1507868
- project
- Post-Antibiotic Futures
- language
- English
- LU publication?
- yes
- id
- c35444f0-989b-4dfd-8b58-44a98426aa8b
- date added to LUP
- 2025-01-09 08:07:15
- date last changed
- 2025-04-11 03:00:15
@article{c35444f0-989b-4dfd-8b58-44a98426aa8b,
abstract = {{Background: Patients’ adherence to antibiotic treatment and related prevention of AMR is significant. Understanding healthcare professionals’ strategies for advising and educating patients in primary care settings is crucial.<br/><br/>Aim: From the perspectives of professionals and patients, to explore how physicians, pharmacists, and nurses educate patients about antibiotic use and antimicrobial resistance in primary care settings.<br/><br/>Methods: A qualitative systematic literature review was conducted in MEDLINE, EMBASE, CINAHL Complete, Eric, SocINDEX, PsycInfo, Web of Science and Scopus. The study included 102 publications, followed PRISMA recommendations and was registered in PROSPERO (reg.no. CRD4202455761). The studies were screened and selected based on specific inclusion and exclusion criteria using Covidence. Quality appraisal followed the Critical Appraisal Skills Program (CASP) qualitative study checklist. Data were extracted, and the analysis consisted of a descriptive numerical summary analysis and a qualitative thematic analysis.<br/><br/>Results: The analyzed studies spanned multiple countries and settings and included perspectives of primary care physicians, pharmacists, nurses and patients. Two main themes emerged: (1) Relationships between professionals and patients influenced educational strategies, showing that trust and rapport between healthcare professionals and patients played a crucial role in shaping educational strategies around antibiotic use; (2) The organizational structures challenged professionals in guiding and educating patients, highlighting how limited resources, time constraints, and system-level pressures hindered healthcare professionals’ ability to provide consistent and effective education. Often, structural challenges led to not educating the patients on the risks of antibiotic misuse and antimicrobial resistance. The use of delayed prescriptions emerged as a strategy for improved AMR stewardship and to meet patients’ expectations for antibiotic treatment, though it raised concerns about undermining professional responsibility and authority in ensuring appropriate antibiotic use.<br/><br/>Conclusion: Healthcare professionals’ role in educating patients about antibiotic use and AMR in primary care settings was complex, with different challenges faced by nurses, pharmacists and primary care physicians. These challenges extended beyond the clinical level, including relational, social and structural factors. Power dynamics, trust issues, and time pressures often hindered effective education on antibiotic use. Addressing gaps in education on antibiotic use and AMR requires acknowledging these multifaceted challenges, with future efforts focusing on better supporting healthcare professionals in this context.<br/><br/>Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD4202455761.}},
author = {{Balea, Lavinia Bianca and Gulestø, Ragnhild Julante Andersen and Xu, Hongxuan and Glasdam, Stinne}},
issn = {{2813-2467}},
keywords = {{antimicrobial resistance; patient education; primary care; professionals; qualitative systematic literature review; pharmacists; physicians; general practitioners; nurses; AMR stewardship; antibiotics}},
language = {{eng}},
month = {{01}},
publisher = {{Frontiers Media S. A.}},
series = {{Frontiers in Antibiotics}},
title = {{Physicians’, pharmacists’, and nurses’ education of patients about antibiotic use and antimicrobial resistance in primary care settings: a qualitative systematic literature review}},
url = {{http://dx.doi.org/10.3389/frabi.2024.1507868}},
doi = {{10.3389/frabi.2024.1507868}},
volume = {{3}},
year = {{2025}},
}