Long‐term follow‐up of laser trabeculoplasty in multi‐treated glaucoma patients
(2024) In Acta Ophthalmologica 102(2). p.179-185- Abstract
- Purpose
To evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).
Methods
Patients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60-month study period. Our previous report on 12 months follow-up data revealed no effect of LTP in eyes having an IOP
Results
Before LTP, the mean IOP ± standard deviation in all 152 study-eyes of 122 multi-treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to... (More) - Purpose
To evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).
Methods
Patients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60-month study period. Our previous report on 12 months follow-up data revealed no effect of LTP in eyes having an IOP
Results
Before LTP, the mean IOP ± standard deviation in all 152 study-eyes of 122 multi-treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to follow-up during the 60 months. After exclusion of eyes that received increased therapy during follow-up, the IOP was significantly reduced at all visits up to 48 months in eyes with pre-LTP IOP ≥15 mmHg; 2.6 ± 3.1 mmHg at 1 month and 1.7 ± 2.8 mmHg at 48 months, n = 56 and 48, respectively. No significant IOP reduction was seen in eyes with pre-LTP IOP
Conclusion
LTP performed in multi-treated patients may provide a useful IOP reduction that is maintained over several years. This was true on a group level when the initial IOP was ≥15 mmHg, but if the pre-laser IOP was lower than that, chances of LTP success were small. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/c43135df-13a2-49bc-8297-236b30eb1855
- author
- Rasmuson, Erika ; Bengtsson, Boel LU ; Lindén, Christina ; Heijl, Anders LU ; Aspberg, Johan LU ; ANDERSSON GEIMER, SABINA LU and Johannesson, Gauti LU
- organization
- publishing date
- 2024-03
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Ophthalmologica
- volume
- 102
- issue
- 2
- pages
- 7 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85161487517
- pmid:37278271
- ISSN
- 1755-3768
- DOI
- 10.1111/aos.15718
- language
- English
- LU publication?
- yes
- id
- c43135df-13a2-49bc-8297-236b30eb1855
- date added to LUP
- 2023-08-14 15:30:34
- date last changed
- 2024-08-28 10:05:44
@article{c43135df-13a2-49bc-8297-236b30eb1855, abstract = {{Purpose<br/>To evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).<br/><br/>Methods<br/>Patients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60-month study period. Our previous report on 12 months follow-up data revealed no effect of LTP in eyes having an IOP <br/>Results<br/>Before LTP, the mean IOP ± standard deviation in all 152 study-eyes of 122 multi-treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to follow-up during the 60 months. After exclusion of eyes that received increased therapy during follow-up, the IOP was significantly reduced at all visits up to 48 months in eyes with pre-LTP IOP ≥15 mmHg; 2.6 ± 3.1 mmHg at 1 month and 1.7 ± 2.8 mmHg at 48 months, n = 56 and 48, respectively. No significant IOP reduction was seen in eyes with pre-LTP IOP <br/>Conclusion<br/>LTP performed in multi-treated patients may provide a useful IOP reduction that is maintained over several years. This was true on a group level when the initial IOP was ≥15 mmHg, but if the pre-laser IOP was lower than that, chances of LTP success were small.}}, author = {{Rasmuson, Erika and Bengtsson, Boel and Lindén, Christina and Heijl, Anders and Aspberg, Johan and ANDERSSON GEIMER, SABINA and Johannesson, Gauti}}, issn = {{1755-3768}}, language = {{eng}}, number = {{2}}, pages = {{179--185}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Ophthalmologica}}, title = {{Long‐term follow‐up of laser trabeculoplasty in multi‐treated glaucoma patients}}, url = {{http://dx.doi.org/10.1111/aos.15718}}, doi = {{10.1111/aos.15718}}, volume = {{102}}, year = {{2024}}, }