Evaluation of renal function parameters with simultaneously administered 99mTc-DTPA and 131I-hippuran
(1983) In European Journal Of Nuclear Medicine 8(2). p.65-71- Abstract
The present study aimed at comparing two renal function tests using 99mTc-DTPA (diethylene triamine penta acetic acid) and 131I-labeled hippuran (o-hippuric acid). A mixture of 80 Mbq 99mTc-DTPA and 7.4 MBq 131I-hippuran in a total volume of 1.5 ml or less was injected into an arm-vein. Both radiopharmaceuticals have identical intitial distributions in the blood pool when injected in this manner. Seventy-two patients were studied with the present dual radionuclide technique. The following parameters were derived from the renogram: area under curve, uptake ratio, Tmax, decrease ratio, excretion ratio, and rate of decrease. The parameters for 99mTc-DTPA and... (More)
The present study aimed at comparing two renal function tests using 99mTc-DTPA (diethylene triamine penta acetic acid) and 131I-labeled hippuran (o-hippuric acid). A mixture of 80 Mbq 99mTc-DTPA and 7.4 MBq 131I-hippuran in a total volume of 1.5 ml or less was injected into an arm-vein. Both radiopharmaceuticals have identical intitial distributions in the blood pool when injected in this manner. Seventy-two patients were studied with the present dual radionuclide technique. The following parameters were derived from the renogram: area under curve, uptake ratio, Tmax, decrease ratio, excretion ratio, and rate of decrease. The parameters for 99mTc-DTPA and 131I-hippuran were compared for various kidney groups. Generally the renographic parameters were well correlated. Apart from the systematic differences due to different modes of renal excretion, the curve patterns virtually agreed. The differences that were observed between the two tracers lacked clinical significance.
(Less)
- author
- Kempi, V.
and Persson, B. R.R.
LU
- organization
- publishing date
- 1983-02-01
- type
- Contribution to journal
- publication status
- published
- in
- European Journal Of Nuclear Medicine
- volume
- 8
- issue
- 2
- pages
- 7 pages
- publisher
- Springer
- external identifiers
-
- scopus:0020538307
- pmid:6341067
- ISSN
- 0340-6997
- DOI
- 10.1007/BF00252558
- language
- English
- LU publication?
- yes
- id
- c7eeb942-5903-4a22-8562-23883d398dba
- date added to LUP
- 2020-05-07 21:29:31
- date last changed
- 2025-01-10 12:43:26
@article{c7eeb942-5903-4a22-8562-23883d398dba, abstract = {{<p>The present study aimed at comparing two renal function tests using <sup>99m</sup>Tc-DTPA (diethylene triamine penta acetic acid) and <sup>131</sup>I-labeled hippuran (o-hippuric acid). A mixture of 80 Mbq <sup>99m</sup>Tc-DTPA and 7.4 MBq <sup>131</sup>I-hippuran in a total volume of 1.5 ml or less was injected into an arm-vein. Both radiopharmaceuticals have identical intitial distributions in the blood pool when injected in this manner. Seventy-two patients were studied with the present dual radionuclide technique. The following parameters were derived from the renogram: area under curve, uptake ratio, T<sub>max</sub>, decrease ratio, excretion ratio, and rate of decrease. The parameters for <sup>99m</sup>Tc-DTPA and <sup>131</sup>I-hippuran were compared for various kidney groups. Generally the renographic parameters were well correlated. Apart from the systematic differences due to different modes of renal excretion, the curve patterns virtually agreed. The differences that were observed between the two tracers lacked clinical significance.</p>}}, author = {{Kempi, V. and Persson, B. R.R.}}, issn = {{0340-6997}}, language = {{eng}}, month = {{02}}, number = {{2}}, pages = {{65--71}}, publisher = {{Springer}}, series = {{European Journal Of Nuclear Medicine}}, title = {{Evaluation of renal function parameters with simultaneously administered <sup>99m</sup>Tc-DTPA and <sup>131</sup>I-hippuran}}, url = {{http://dx.doi.org/10.1007/BF00252558}}, doi = {{10.1007/BF00252558}}, volume = {{8}}, year = {{1983}}, }