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Intraoperative transfusion practices in Europe

Meier, J ; Filipescu, D ; Kozek-Langenecker, S ; Llau Pitarch, J ; Mallet, S ; Martus, P and Matot, I (2016) In British Journal of Anaesthesia 116(2). p.255-261
Abstract
Background
Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe.
Methods
We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013.
Results
The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially... (More)
Background
Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe.
Methods
We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013.
Results
The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl−1 and increased to 9.8 (1.8) g dl−1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2).
Conclusion
Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7–9 g dl−1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold. (Less)
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author collaboration
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Anaesthesia
volume
116
issue
2
pages
255 - 261
publisher
Elsevier
external identifiers
  • scopus:84961917688
ISSN
1471-6771
DOI
10.1093/bja/aev456
language
English
LU publication?
no
id
caf0f6db-a704-4965-a6e5-18d1a7e8f75f
date added to LUP
2021-02-08 02:21:04
date last changed
2022-04-19 04:30:10
@article{caf0f6db-a704-4965-a6e5-18d1a7e8f75f,
  abstract     = {{Background<br/>Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe.<br/>Methods<br/>We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013.<br/>Results<br/>The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl−1 and increased to 9.8 (1.8) g dl−1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2).<br/>Conclusion<br/>Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7–9 g dl−1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold.}},
  author       = {{Meier, J and Filipescu, D and Kozek-Langenecker, S and Llau Pitarch, J and Mallet, S and Martus, P and Matot, I}},
  issn         = {{1471-6771}},
  language     = {{eng}},
  month        = {{02}},
  number       = {{2}},
  pages        = {{255--261}},
  publisher    = {{Elsevier}},
  series       = {{British Journal of Anaesthesia}},
  title        = {{Intraoperative transfusion practices in Europe}},
  url          = {{http://dx.doi.org/10.1093/bja/aev456}},
  doi          = {{10.1093/bja/aev456}},
  volume       = {{116}},
  year         = {{2016}},
}