Tuning the protein phosphorylation by receptor type protein tyrosine phosphatase epsilon (PTPRE) in normal and cancer cells
(2019) In Journal of Cancer 10(1). p.105-111- Abstract
Tyrosine phosphorylation is an important post-translation modification of proteins that is controlled by tyrosine kinases and phosphatases. Disruption of the balance between the activity of tyrosine kinases and phosphatases may result in diseases. Receptor type protein tyrosine phosphatase epsilon (PTPRE) is closely related with receptor type protein tyrosine phosphatase alpha (PTPRA). PTPRE has been studied in osteoclast cells, nerve cells, hematopoietic cells, cancer cells and others, and it has different functions among various tissues. In this review, we summarized the current knowledge about the regulation of PTPRE on cellular signal transduction and its function under normal and pathological conditions.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d48bf806-ff9d-4896-b4c9-0262d807ce42
- author
- Liang, Jinping ; Shi, Jun ; Wang, Na ; Zhao, Hui and Sun, Jianmin LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cancer, PTPRE, Signaling, Tyrosine phosphatase
- in
- Journal of Cancer
- volume
- 10
- issue
- 1
- pages
- 7 pages
- publisher
- Ivyspring International Publisher
- external identifiers
-
- scopus:85059513100
- pmid:30662530
- ISSN
- 1837-9664
- DOI
- 10.7150/jca.27633
- language
- English
- LU publication?
- yes
- id
- d48bf806-ff9d-4896-b4c9-0262d807ce42
- date added to LUP
- 2019-01-22 14:54:48
- date last changed
- 2024-09-18 11:26:03
@article{d48bf806-ff9d-4896-b4c9-0262d807ce42, abstract = {{<p>Tyrosine phosphorylation is an important post-translation modification of proteins that is controlled by tyrosine kinases and phosphatases. Disruption of the balance between the activity of tyrosine kinases and phosphatases may result in diseases. Receptor type protein tyrosine phosphatase epsilon (PTPRE) is closely related with receptor type protein tyrosine phosphatase alpha (PTPRA). PTPRE has been studied in osteoclast cells, nerve cells, hematopoietic cells, cancer cells and others, and it has different functions among various tissues. In this review, we summarized the current knowledge about the regulation of PTPRE on cellular signal transduction and its function under normal and pathological conditions.</p>}}, author = {{Liang, Jinping and Shi, Jun and Wang, Na and Zhao, Hui and Sun, Jianmin}}, issn = {{1837-9664}}, keywords = {{Cancer; PTPRE; Signaling; Tyrosine phosphatase}}, language = {{eng}}, number = {{1}}, pages = {{105--111}}, publisher = {{Ivyspring International Publisher}}, series = {{Journal of Cancer}}, title = {{Tuning the protein phosphorylation by receptor type protein tyrosine phosphatase epsilon (PTPRE) in normal and cancer cells}}, url = {{http://dx.doi.org/10.7150/jca.27633}}, doi = {{10.7150/jca.27633}}, volume = {{10}}, year = {{2019}}, }