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Ventricular kinetic energy in young fontan patients

Sjöberg, P. LU orcid ; Heiberg, E. LU orcid ; Wingren, P. LU ; Arheden, H. LU ; Liuba, P. LU and Carlsson, Marcus LU (2016) 50th Annual Meeting of the Association for European Paediatric and Congenital Cardiology In Cardiology in the Young 26(Suppl 1). p.64-64
Abstract
Introduction: Four-dimensional (4D) flow magnetic resonance imaging (MRI) enables kinetic energy (KE) quantification of intraventricular blood flow. In this study we aimed to quantify the KE in in patients with univentricular heart and to assess the change in the KE after different types of interventions. Methods: 4D flow MRI was acquired in patients with Fontan circulation (n=12; median age 12, range 3-29 years) and in healthy volunteers (n =8; median age 26, range 23-36 years). MRI was repeated after transcatheter embolization of significant aortopulmonary collaterals (APC; n = 1), after stenting of left pulmonary artery (n=1) and after surgical replacement of hepatic flow tunnel with a Y graft due to significant central pulmonary artery... (More)
Introduction: Four-dimensional (4D) flow magnetic resonance imaging (MRI) enables kinetic energy (KE) quantification of intraventricular blood flow. In this study we aimed to quantify the KE in in patients with univentricular heart and to assess the change in the KE after different types of interventions. Methods: 4D flow MRI was acquired in patients with Fontan circulation (n=12; median age 12, range 3-29 years) and in healthy volunteers (n =8; median age 26, range 23-36 years). MRI was repeated after transcatheter embolization of significant aortopulmonary collaterals (APC; n = 1), after stenting of left pulmonary artery (n=1) and after surgical replacement of hepatic flow tunnel with a Y graft due to significant central pulmonary artery stenosis with secondary formation of arteriovenous (AV) fistulas in the right lung (n= 1). Intraventricular KE was calculated throughout the cardiac cycle and indexed to stroke volume (SV). Results: The systole/diastole ratio of KE in Fontan patients was similar to the ratio of the controls' left ventricle (LV) or right ventricle (RV) depending on the ventricular morphology (Coheńs kappa =1.0). Peak systolic KE/SV did not differ in patients compared to the LV in controls (0.016 ± 0.006 mJ/ml vs 0.020 ±0.004 mJ/ml, p= 0.09). Peak diastolic KE/SV in Fontan patients was lower than in the LV of the control group (0.028 ±0.010 vs 0.057± 0.011 mJ/ml, p (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
adolescent, adult, arteriovenous fistula, artificial embolization, child, clinical article, control group, controlled study, diastole, follow up, heart contraction, heart cycle, heart left ventricle, heart right ventricle, heart single ventricle, heart stroke volume, human, inhibition kinetics, liver blood flow, morphology, nuclear magnetic resonance imaging, pulmonary artery stenosis, quantitative study, right lung, stent, surgery, volunteer
in
Cardiology in the Young
volume
26
issue
Suppl 1
pages
1 pages
publisher
Cambridge University Press
conference name
50th Annual Meeting of the Association for European Paediatric and Congenital Cardiology
conference location
Italy
conference dates
2016-06-01 - 2016-06-04
ISSN
1467-1107
DOI
10.1017/S1047951116000500
language
English
LU publication?
yes
id
e8812dbf-c4e8-405f-9f47-6dc3149e2e9e
date added to LUP
2017-07-21 10:36:03
date last changed
2025-04-04 13:51:19
@misc{e8812dbf-c4e8-405f-9f47-6dc3149e2e9e,
  abstract     = {{Introduction: Four-dimensional (4D) flow magnetic resonance imaging (MRI) enables kinetic energy (KE) quantification of intraventricular blood flow. In this study we aimed to quantify the KE in in patients with univentricular heart and to assess the change in the KE after different types of interventions. Methods: 4D flow MRI was acquired in patients with Fontan circulation (n=12; median age 12, range 3-29 years) and in healthy volunteers (n =8; median age 26, range 23-36 years). MRI was repeated after transcatheter embolization of significant aortopulmonary collaterals (APC; n = 1), after stenting of left pulmonary artery (n=1) and after surgical replacement of hepatic flow tunnel with a Y graft due to significant central pulmonary artery stenosis with secondary formation of arteriovenous (AV) fistulas in the right lung (n= 1). Intraventricular KE was calculated throughout the cardiac cycle and indexed to stroke volume (SV). Results: The systole/diastole ratio of KE in Fontan patients was similar to the ratio of the controls' left ventricle (LV) or right ventricle (RV) depending on the ventricular morphology (Coheńs kappa =1.0). Peak systolic KE/SV did not differ in patients compared to the LV in controls (0.016 ± 0.006 mJ/ml vs 0.020 ±0.004 mJ/ml, p= 0.09). Peak diastolic KE/SV in Fontan patients was lower than in the LV of the control group (0.028 ±0.010 vs 0.057± 0.011 mJ/ml, p}},
  author       = {{Sjöberg, P. and Heiberg, E. and Wingren, P. and Arheden, H. and Liuba, P. and Carlsson, Marcus}},
  issn         = {{1467-1107}},
  keywords     = {{adolescent; adult; arteriovenous fistula; artificial embolization; child; clinical article; control group; controlled study; diastole; follow up; heart contraction; heart cycle; heart left ventricle; heart right ventricle; heart single ventricle; heart stroke volume; human; inhibition kinetics; liver blood flow; morphology; nuclear magnetic resonance imaging; pulmonary artery stenosis; quantitative study; right lung; stent; surgery; volunteer}},
  language     = {{eng}},
  month        = {{05}},
  note         = {{Conference Abstract}},
  number       = {{Suppl 1}},
  pages        = {{64--64}},
  publisher    = {{Cambridge University Press}},
  series       = {{Cardiology in the Young}},
  title        = {{Ventricular kinetic energy in young fontan patients}},
  url          = {{http://dx.doi.org/10.1017/S1047951116000500}},
  doi          = {{10.1017/S1047951116000500}},
  volume       = {{26}},
  year         = {{2016}},
}