Effects of pancreozymin and secretin on insulin release and the role of the exocrine pancreas
(1974) In Diabetologia 10(5). p.407-409- Abstract
Mouse pancreatic islets microdissected free from, or surrounded by, exocrine cells were used to study the effects of secretin and choleeystokinm-pancreozymin on insulin release. Both secretin and cholecystokinin-pancreozymin potentiated glucose-stimulated insulin release regardless of whether exocrine cells were present. The results fail to support the idea that the presence of the exocrine parenchyma is essential for elicitation of insulin release by these gastrointestinal hormones.
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https://lup.lub.lu.se/record/f4577e7f-c8cf-4c15-8cde-8bdf3b442f11
- author
- Danielsson, Å and Lernmark, Å LU
- publishing date
- 1974-10-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- exocrine cells, Insulin release, mouse islets, pancreozymin, secretin
- in
- Diabetologia
- volume
- 10
- issue
- 5
- pages
- 3 pages
- publisher
- Springer
- external identifiers
-
- scopus:0016210330
- pmid:4615962
- ISSN
- 0012-186X
- DOI
- 10.1007/BF01221629
- language
- English
- LU publication?
- no
- id
- f4577e7f-c8cf-4c15-8cde-8bdf3b442f11
- date added to LUP
- 2019-09-18 12:16:47
- date last changed
- 2024-03-13 08:00:39
@article{f4577e7f-c8cf-4c15-8cde-8bdf3b442f11, abstract = {{<p>Mouse pancreatic islets microdissected free from, or surrounded by, exocrine cells were used to study the effects of secretin and choleeystokinm-pancreozymin on insulin release. Both secretin and cholecystokinin-pancreozymin potentiated glucose-stimulated insulin release regardless of whether exocrine cells were present. The results fail to support the idea that the presence of the exocrine parenchyma is essential for elicitation of insulin release by these gastrointestinal hormones.</p>}}, author = {{Danielsson, Å and Lernmark, Å}}, issn = {{0012-186X}}, keywords = {{exocrine cells; Insulin release; mouse islets; pancreozymin; secretin}}, language = {{eng}}, month = {{10}}, number = {{5}}, pages = {{407--409}}, publisher = {{Springer}}, series = {{Diabetologia}}, title = {{Effects of pancreozymin and secretin on insulin release and the role of the exocrine pancreas}}, url = {{http://dx.doi.org/10.1007/BF01221629}}, doi = {{10.1007/BF01221629}}, volume = {{10}}, year = {{1974}}, }