Suction cup on a piston-based chest compression device improves coronary perfusion pressure and cerebral oxygenation during experimental cardiopulmonary resuscitation
Mälberg, Johan ; Smekal, David ; Marchesi, Silvia LU
; Lipcsey, Miklos
and Rubertsson, Sten
(2022)
In Resuscitation Plus
12.
- Abstract
- Introduction: The presented study aimed to investigate whether a mechanical chest compression piston device with a suction cup assisting chest recoil could impact the hemodynamic status when compared to a bare piston during cardiopulmonary resuscitation.
Methods: 16 piglets were anesthetized and randomized into 2 groups. After 3 minutes of induced ventricular fibrillation, a LUCAS 3 device was used to perform chest compressions, in one group a suction cup was mounted on the device's piston, while in the other group, compressions were performed by the bare piston. The device was used in 30:2 mode and the animals were manually ventilated. Endpoints of the study were: end tidal carbon dioxide, coronary and cerebral perfusion... (More) - Introduction: The presented study aimed to investigate whether a mechanical chest compression piston device with a suction cup assisting chest recoil could impact the hemodynamic status when compared to a bare piston during cardiopulmonary resuscitation.
Methods: 16 piglets were anesthetized and randomized into 2 groups. After 3 minutes of induced ventricular fibrillation, a LUCAS 3 device was used to perform chest compressions, in one group a suction cup was mounted on the device's piston, while in the other group, compressions were performed by the bare piston. The device was used in 30:2 mode and the animals were manually ventilated. Endpoints of the study were: end tidal carbon dioxide, coronary and cerebral perfusion pressures, and brain oxygenation (measured using near infrared spectroscopy). At the end of the protocol, the animals that got a return to spontaneous circulation were observed for 60 minutes, then euthanized.
Results: No difference was found in end tidal carbon dioxide or tidal volumes. Coronary perfusion pressure and cerebral oxygenation were higher in the Suction cup group over the entire experiment time, while cerebral perfusion pressure was higher only in the last 5 minutes of CPR. A passive tidal volume (air going in and out the airways during compressions) was detected and found correlated to end tidal carbon dioxide.
Conclusions: The use of a suction cup on a piston-based chest compression device did not increase end tidal carbon dioxide, but it was associated to a higher coronary perfusion pressure.
(Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/f4cf4454-2329-46b4-af63-6b24e2413bb8
- author
- Mälberg, Johan
; Smekal, David
; Marchesi, Silvia
LU
; Lipcsey, Miklos
and Rubertsson, Sten
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Resuscitation Plus
- volume
- 12
- article number
- 100311
- publisher
- Elsevier
- external identifiers
-
- scopus:85139051996
- ISSN
- 2666-5204
- DOI
- 10.1016/j.resplu.2022.100311
- language
- English
- LU publication?
- no
- id
- f4cf4454-2329-46b4-af63-6b24e2413bb8
- date added to LUP
- 2025-03-07 13:36:43
- date last changed
- 2025-04-04 13:57:02
@article{f4cf4454-2329-46b4-af63-6b24e2413bb8,
abstract = {{Introduction: The presented study aimed to investigate whether a mechanical chest compression piston device with a suction cup assisting chest recoil could impact the hemodynamic status when compared to a bare piston during cardiopulmonary resuscitation.<br/><br/>Methods: 16 piglets were anesthetized and randomized into 2 groups. After 3 minutes of induced ventricular fibrillation, a LUCAS 3 device was used to perform chest compressions, in one group a suction cup was mounted on the device's piston, while in the other group, compressions were performed by the bare piston. The device was used in 30:2 mode and the animals were manually ventilated. Endpoints of the study were: end tidal carbon dioxide, coronary and cerebral perfusion pressures, and brain oxygenation (measured using near infrared spectroscopy). At the end of the protocol, the animals that got a return to spontaneous circulation were observed for 60 minutes, then euthanized.<br/><br/>Results: No difference was found in end tidal carbon dioxide or tidal volumes. Coronary perfusion pressure and cerebral oxygenation were higher in the Suction cup group over the entire experiment time, while cerebral perfusion pressure was higher only in the last 5 minutes of CPR. A passive tidal volume (air going in and out the airways during compressions) was detected and found correlated to end tidal carbon dioxide.<br/><br/>Conclusions: The use of a suction cup on a piston-based chest compression device did not increase end tidal carbon dioxide, but it was associated to a higher coronary perfusion pressure.<br/>}},
author = {{Mälberg, Johan and Smekal, David and Marchesi, Silvia and Lipcsey, Miklos and Rubertsson, Sten}},
issn = {{2666-5204}},
language = {{eng}},
publisher = {{Elsevier}},
series = {{Resuscitation Plus}},
title = {{Suction cup on a piston-based chest compression device improves coronary perfusion pressure and cerebral oxygenation during experimental cardiopulmonary resuscitation}},
url = {{http://dx.doi.org/10.1016/j.resplu.2022.100311}},
doi = {{10.1016/j.resplu.2022.100311}},
volume = {{12}},
year = {{2022}},
}