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Magnesium deficiency in IDDM related to level of glycosylated hemoglobin

Sjögren, Anders ; Florén, Claes-Henrik LU and Nilsson, Åke LU (1986) In Diabetes 35(4). p.459-463
Abstract (Swedish)
Magnesium and potassium were analyzed in plasma, erythrocytes, and urine collected during 24 h and in muscle biopsies from 25 subjects with insulin-dependent, type I diabetes mellitus (IDDM). Magnesium was also measured in mononuclear cells. The results were compared with those of 28 healthy controls, and were also correlated with the degree of diabetic control as estimated by analysis of the level of glycosylated hemoglobin (HbA1c). Subjects with IDDM had significantly lower muscle (P less than 0.01) and plasma (P less than 0.001) concentrations of magnesium compared with those of healthy controls. The HbA1c levels correlated significantly with the concentrations of magnesium in muscle (r = -0.62, P less than 0.001), plasma (r = -0.62, P... (More)
Magnesium and potassium were analyzed in plasma, erythrocytes, and urine collected during 24 h and in muscle biopsies from 25 subjects with insulin-dependent, type I diabetes mellitus (IDDM). Magnesium was also measured in mononuclear cells. The results were compared with those of 28 healthy controls, and were also correlated with the degree of diabetic control as estimated by analysis of the level of glycosylated hemoglobin (HbA1c). Subjects with IDDM had significantly lower muscle (P less than 0.01) and plasma (P less than 0.001) concentrations of magnesium compared with those of healthy controls. The HbA1c levels correlated significantly with the concentrations of magnesium in muscle (r = -0.62, P less than 0.001), plasma (r = -0.62, P less than 0.001), and mononuclear cells (r = -0.47, P less than 0.05). The results indicate that some patients with IDDM have lowered contents of magnesium in striated muscular and/or plasma, and that those parameters are dependent on the degree of diabetic control. (Less)
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author
; and
publishing date
type
Contribution to journal
publication status
published
in
Diabetes
volume
35
issue
4
pages
5 pages
publisher
American Diabetes Association Inc.
external identifiers
  • scopus:0022450297
ISSN
1939-327X
language
Swedish
LU publication?
no
id
f9353c1e-1541-4fdd-b6a2-42f647cefad6
date added to LUP
2019-05-26 20:21:45
date last changed
2023-05-22 04:00:38
@article{f9353c1e-1541-4fdd-b6a2-42f647cefad6,
  abstract     = {{Magnesium and potassium were analyzed in plasma, erythrocytes, and urine collected during 24 h and in muscle biopsies from 25 subjects with insulin-dependent, type I diabetes mellitus (IDDM). Magnesium was also measured in mononuclear cells. The results were compared with those of 28 healthy controls, and were also correlated with the degree of diabetic control as estimated by analysis of the level of glycosylated hemoglobin (HbA1c). Subjects with IDDM had significantly lower muscle (P less than 0.01) and plasma (P less than 0.001) concentrations of magnesium compared with those of healthy controls. The HbA1c levels correlated significantly with the concentrations of magnesium in muscle (r = -0.62, P less than 0.001), plasma (r = -0.62, P less than 0.001), and mononuclear cells (r = -0.47, P less than 0.05). The results indicate that some patients with IDDM have lowered contents of magnesium in striated muscular and/or plasma, and that those parameters are dependent on the degree of diabetic control.}},
  author       = {{Sjögren, Anders and Florén, Claes-Henrik and Nilsson, Åke}},
  issn         = {{1939-327X}},
  language     = {{swe}},
  month        = {{04}},
  number       = {{4}},
  pages        = {{459--463}},
  publisher    = {{American Diabetes Association Inc.}},
  series       = {{Diabetes}},
  title        = {{Magnesium deficiency in IDDM related to level of glycosylated hemoglobin}},
  volume       = {{35}},
  year         = {{1986}},
}