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Respiratory symptoms among epoxy-exposed workers in the wind turbine industry : a cross-sectional study

Eggertsen, Christine Marie ; Dalbøge, Annett ; Clausen, Per Axel ; Bønløkke, Jakob ; Kolstad, Henrik Albert ; Isaksson, Marléne LU ; Carstensen, Ole ; Schlünssen, Vivi and Christiansen, Alexandra Golabek (2026) In Annals of Work Exposures and Health 70(1).
Abstract

Objectives The aim was to estimate the prevalence and risk of respiratory symptoms among workers exposed to epoxy resin systems in the wind turbine industry. Methods We conducted a cross-sectional study including 180 epoxy-exposed production workers from two Danish wind turbine blade factories and 41 non-exposed office workers. Respiratory symptoms were defined as having two or more symptoms (i.e. wheezing in chest, waking up with chest tightness, shortness of breath, attack of coughing, or asthma attack) within the last 12 mo. Epoxy exposure was defined as exposure status (epoxy-exposed production worker or non-exposed office worker) and years of epoxy-exposure (years of employment as production worker). Epoxy skin sensitization status... (More)

Objectives The aim was to estimate the prevalence and risk of respiratory symptoms among workers exposed to epoxy resin systems in the wind turbine industry. Methods We conducted a cross-sectional study including 180 epoxy-exposed production workers from two Danish wind turbine blade factories and 41 non-exposed office workers. Respiratory symptoms were defined as having two or more symptoms (i.e. wheezing in chest, waking up with chest tightness, shortness of breath, attack of coughing, or asthma attack) within the last 12 mo. Epoxy exposure was defined as exposure status (epoxy-exposed production worker or non-exposed office worker) and years of epoxy-exposure (years of employment as production worker). Epoxy skin sensitization status was obtained through a patch-test. The association between epoxy-exposure and respiratory symptoms was estimated using modified Poisson regression (prevalence ratio (PR)) adjusting for smoking and age. Results A total of 13.3% of the epoxy-exposed production workers and 4.9% of non-exposed office workers reported two or more respiratory symptoms (PRadj=1.8, 95% CI 0.4-9.5). For years of exposure, PRadj values were 1.2 (<1 yr), 1.0 (≥1-<5 yr), and 2.6 (≥5 yr). Higher PRadj were found among men. Epoxy-sensitized production workers had a PRadj of 0.4, while non-sensitized workers had a PRadj of 1.9, compared to non-exposed office workers. Conclusion Epoxy-exposed production workers showed a tendency to report respiratory symptoms more often than nonexposed office workers. However, we found no clear association between exposure duration and symptoms. Further studies are highly warranted to evaluate the potential association between epoxy exposure and respiratory symptoms.

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; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
asthma, lung disease, occupational exposure, respiratory symptom, work
in
Annals of Work Exposures and Health
volume
70
issue
1
article number
wxaf045
publisher
Oxford University Press
external identifiers
  • scopus:105028266400
  • pmid:40971920
ISSN
2398-7308
DOI
10.1093/annweh/wxaf045
language
English
LU publication?
yes
additional info
Publisher Copyright: © The Author(s) 2025. Published by Oxford University Press on behalf of the British Occupational Hygiene Society. All rights reserved.
id
fa909e6b-b007-4e4e-a65f-2d94c446aab7
date added to LUP
2026-02-25 16:01:40
date last changed
2026-02-25 16:02:31
@article{fa909e6b-b007-4e4e-a65f-2d94c446aab7,
  abstract     = {{<p>Objectives The aim was to estimate the prevalence and risk of respiratory symptoms among workers exposed to epoxy resin systems in the wind turbine industry. Methods We conducted a cross-sectional study including 180 epoxy-exposed production workers from two Danish wind turbine blade factories and 41 non-exposed office workers. Respiratory symptoms were defined as having two or more symptoms (i.e. wheezing in chest, waking up with chest tightness, shortness of breath, attack of coughing, or asthma attack) within the last 12 mo. Epoxy exposure was defined as exposure status (epoxy-exposed production worker or non-exposed office worker) and years of epoxy-exposure (years of employment as production worker). Epoxy skin sensitization status was obtained through a patch-test. The association between epoxy-exposure and respiratory symptoms was estimated using modified Poisson regression (prevalence ratio (PR)) adjusting for smoking and age. Results A total of 13.3% of the epoxy-exposed production workers and 4.9% of non-exposed office workers reported two or more respiratory symptoms (PR<sub>adj</sub>=1.8, 95% CI 0.4-9.5). For years of exposure, PR<sub>adj</sub> values were 1.2 (&lt;1 yr), 1.0 (≥1-&lt;5 yr), and 2.6 (≥5 yr). Higher PR<sub>adj</sub> were found among men. Epoxy-sensitized production workers had a PR<sub>adj</sub> of 0.4, while non-sensitized workers had a PR<sub>adj</sub> of 1.9, compared to non-exposed office workers. Conclusion Epoxy-exposed production workers showed a tendency to report respiratory symptoms more often than nonexposed office workers. However, we found no clear association between exposure duration and symptoms. Further studies are highly warranted to evaluate the potential association between epoxy exposure and respiratory symptoms.</p>}},
  author       = {{Eggertsen, Christine Marie and Dalbøge, Annett and Clausen, Per Axel and Bønløkke, Jakob and Kolstad, Henrik Albert and Isaksson, Marléne and Carstensen, Ole and Schlünssen, Vivi and Christiansen, Alexandra Golabek}},
  issn         = {{2398-7308}},
  keywords     = {{asthma; lung disease; occupational exposure; respiratory symptom; work}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1}},
  publisher    = {{Oxford University Press}},
  series       = {{Annals of Work Exposures and Health}},
  title        = {{Respiratory symptoms among epoxy-exposed workers in the wind turbine industry : a cross-sectional study}},
  url          = {{http://dx.doi.org/10.1093/annweh/wxaf045}},
  doi          = {{10.1093/annweh/wxaf045}},
  volume       = {{70}},
  year         = {{2026}},
}