Herwig Schüler

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2020
Mark Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins
Nowak, Kathrin ; Rosenthal, Florian ; Karlberg, Tobias ^LU ; Bütepage, Mareike ; Thorsell, Ann-Gerd ; Dreier, Birgit ; Grossmann, Jonas ; Sobek, Jens ; Imhof, Ralph and Lüscher, Bernhard , et al. (2020) In Nature Communications 11(1).
- Contribution to journal › Article
2019
Mark A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD⁺-Dependent Enzymes
Yuen, Lik Hang ; Dana, Srikanta ; Liu, Yu ; Bloom, Samuel I ; Thorsell, Ann-Gerd ; Neri, Dario ; Donato, Anthony J ; Kireev, Dmitri ; Schüler, Herwig ^LU and Franzini, Raphael M (2019) In Journal of the American Chemical Society 141(13). p.5169-5181
- Contribution to journal › Article
2018
Mark A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity
Kirby, Ilsa T ; Kojic, Ana ; Arnold, Moriah R ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; Vermehren-Schmaedick, Anke ; Sreenivasan, Raashi ; Schultz, Carsten ; Schüler, Herwig ^LU and Cohen, Michael S (2018) In Cell Chemical Biology 25(12). p.12-1553
- Contribution to journal › Article
Mark 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface
Karlberg, Tobias ^LU ; Hornyak, Peter ; Pinto, Ana Filipa ; Milanova, Stefina ; Ebrahimi, Mahsa ; Lindberg, Mikael ; Püllen, Nikolai ; Nordström, Axel ; Löverli, Elinor and Caraballo, Rémi , et al. (2018) In Nature Communications 9(1).
- Contribution to journal › Article
Mark A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition
Favalli, Nicholas ; Biendl, Stefan ; Hartmann, Marco ; Piazzi, Jacopo ; Sladojevich, Filippo ; Gräslund, Susanne ; Brown, Peter J ; Näreoja, Katja ; Schüler, Herwig ^LU and Scheuermann, Jörg , et al. (2018) In ChemMedChem 13(13). p.1303-1307
- Contribution to journal › Article
Mark Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14
Holechek, Jacob ; Lease, Robert ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; McCadden, Caitlin ; Grant, Ryan ; Keen, Abby ; Callahan, Evan ; Schüler, Herwig ^LU and Ferraris, Dana (2018) In Bioorganic & Medicinal Chemistry Letters 28(11). p.2050-2054
- Contribution to journal › Article
Mark Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol
Ekblad, Torun ; Verheugd, Patricia ; Lindgren, Anders E ; Nyman, Tomas ; Elofsson, Mikael and Schüler, Herwig ^LU (2018) In SLAS Discovery 23(4). p.353-362
- Contribution to journal › Article
Mark Structure-activity relationships for inhibitors of Pseudomonas aeruginosa exoenzyme S ADP-ribosyltransferase activity
Saleeb, Michael ; Sundin, Charlotta ; Aglar, Öznur ; Pinto, Ana Filipa ; Ebrahimi, Mahsa ; Forsberg, Åke ; Schüler, Herwig ^LU and Elofsson, Mikael (2018) In European Journal of Medicinal Chemistry 143. p.568-576
- Contribution to journal › Article
2017
Mark Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14
Upton, Kristen ; Meyers, Matthew ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; Holechek, Jacob ; Lease, Robert ; Schey, Garrett ; Wolf, Emily ; Lucente, Adrianna and Schüler, Herwig ^LU , et al. (2017) In Bioorganic & Medicinal Chemistry Letters 27(13). p.2907-2911
- Contribution to journal › Article
Mark Small Molecule Microarray Based Discovery of PARP14 Inhibitors
Peng, Bo ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; Schüler, Herwig ^LU and Yao, Shao Q (2017) In Angewandte Chemie (International edition) 56(1). p.248-253
- Contribution to journal › Article

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