Karl Bacos

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2019
Mark Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets
Hall, Elin ^LU ; Jönsson, Josefine ^LU ; Ofori, Jones K. ^LU ; Volkov, Petr ^LU ; Perfilyev, Alexander ^LU ; Nitert, Marloes Dekker ^LU ; Eliasson, Lena ^LU ; Ling, Charlotte ^LU and Bacos, Karl ^LU (2019) In Diabetes 68(10). p.1965-1974
- Contribution to journal › Article
Mark ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.
Bysani, Madhusudhan ^LU ; Agren, Rasmus ; Davegårdh, Cajsa ^LU ; Volkov, Petr ^LU ; Rönn, Tina ^LU ; Unneberg, Per ; Bacos, Karl ^LU and Ling, Charlotte ^LU (2019) In Scientific Reports 9.
- Contribution to journal › Article
Mark The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis
Backe, Marie Balslev ^LU ; Jin, Chunyu ; Andreone, Luz ; Sankar, Aditya ; Agger, Karl ; Helin, Kristian ; Madsen, Andreas Nygaard ; Poulsen, Steen Seier ; Bysani, Madhusudhan ^LU and Bacos, Karl ^LU , et al. (2019) In Journal of Diabetes Research 2019.
- Contribution to journal › Article
2018
Mark DNA methylation in the pathogenesis of type 2 diabetes in humans
Davegårdh, Cajsa ^LU ; García-Calzón, Sonia ^LU ; Bacos, Karl ^LU and Ling, Charlotte ^LU (2018) In Molecular Metabolism 14. p.12-25
- Contribution to journal › Scientific review
Mark MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation
Daneshpajooh, Mahboubeh ^LU ; Eliasson, Lena ^LU ; Bacos, Karl ^LU and Ling, Charlotte ^LU (2018) In Acta Diabetologica 55(12). p.1231-1235
- Contribution to journal › Article
Mark The effects of high glucose exposure on global gene expression and DNA methylation in human pancreatic islets
Hall, Elin ^LU ; Dekker Nitert, Marloes ^LU ; Volkov, Petr ^LU ; Malmgren, Siri ^LU ; Mulder, Hindrik ^LU ; Bacos, Karl ^LU and Ling, Charlotte ^LU (2018) In Molecular and Cellular Endocrinology 472. p.57-67
- Contribution to journal › Article
Mark Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
Backe, Marie Balslev ^LU ; Andersson, Jan Legaard ; Bacos, Karl ^LU ; Christensen, Dan Ploug ; Hansen, Jakob Bondo ; Dorosz, Jerzy Jòzef ; Gajhede, Michael ; Dahlby, Tina ; Bysani, Madhusudhan ^LU and Kristensen, Line Hyltoft , et al. (2018) In Molecular and Cellular Endocrinology 460. p.47-56
- Contribution to journal › Article
2017
Mark Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity
Keller, Maria ^LU ; Hopp, Lydia ; Liu, Xuanshi ; Wohland, Tobias ; Rohde, Kerstin ^LU ; Cancello, Raffaella ; Klös, Matthias ; Bacos, Karl ^LU ; Kern, Matthias and Eichelmann, Fabian , et al. (2017) In Molecular Metabolism 6(1). p.86-100
- Contribution to journal › Article
Mark Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
Volkov, Petr ^LU ; Bacos, Karl ^LU ; Ofori, Jones K ^LU ; Esguerra, Jonathan Lou S ^LU ; Eliasson, Lena ^LU ; Rönn, Tina ^LU and Ling, Charlotte ^LU (2017) In Diabetes 66(4). p.1074-1085
- Contribution to journal › Article
Mark HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
Daneshpajooh, Mahboubeh ^LU ; Bacos, Karl ^LU ; Bysani, Madhusudhan ^LU ; Bagge, Annika ^LU ; Ottosson Laakso, Emilia ^LU ; Vikman, Petter ^LU ; Eliasson, Lena ^LU ; Mulder, Hindrik ^LU and Ling, Charlotte ^LU (2017) In Diabetologia 60(1). p.116-125
- Contribution to journal › Article