Helena Ågerstam

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2016
Mark IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
Ågerstam, Helena ^LU ; Hansen, Nils ^LU ; von Palffy, Sofia ^LU ; Sandén, Carl ^LU ; Reckzeh, Kristian ^LU ; Karlsson, Christine ^LU ; Lilljebjörn, Henrik ^LU ; Landberg, Niklas ^LU ; Askmyr, Maria ^LU and Högberg, Carl ^LU , et al. (2016) In Blood 128(23). p.2683-2693
- Contribution to journal › Article
2015
Mark IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.
Landberg, Niklas ^LU ; Hansen, Nils ^LU ; Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Lassen, Carin ^LU ; Rissler, Marianne ^LU ; Hansen, H H ; Mustjoki, S ; Järås, Marcus ^LU and Richter, Johan ^LU , et al. (2015) In Leukemia 30(1). p.255-258
- Contribution to journal › Article
Mark Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Ågerstam, Helena ^LU ; Karlsson, Christine ^LU ; Hansen, Nils ^LU ; Sandén, Carl ^LU ; Askmyr, Maria ^LU ; von Palffy, Sofia ^LU ; Högberg, Carl ^LU ; Rissler, Marianne ^LU ; Wunderlich, Mark and Juliusson, Gunnar ^LU , et al. (2015) In Proceedings of the National Academy of Sciences 112(34). p.10786-10791
- Contribution to journal › Article
2014
Mark Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.
Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Lilljebjörn, Henrik ^LU ; Hansen, Nils ^LU ; Karlsson, Christine ^LU ; von Palffy, Sofia ^LU ; Landberg, Niklas ^LU ; Högberg, Carl ^LU ; Lassen, Carin ^LU and Rissler, Marianne ^LU , et al. (2014) In Blood Cancer Journal 4.
- Contribution to journal › Article
Mark RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib.
Lilljebjörn, Henrik ^LU ; Ågerstam, Helena ^LU ; Orsmark Pietras, Christina ^LU ; Rissler, Marianne ^LU ; Ehrencrona, Hans ^LU ; Nilsson, L ; Richter, Johan ^LU and Fioretos, Thoas ^LU (2014) In Leukemia 28(4). p.977-979
- Contribution to journal › Letter
2013
Mark SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function.
Hansen, Nils ^LU ; Ågerstam, Helena ^LU ; Wahlestedt, Martin ^LU ; Landberg, Niklas ^LU ; Askmyr, Maria ^LU ; Ehinger, Mats ^LU ; Rissler, Marianne ^LU ; Lilljebjörn, Henrik ^LU ; Johnels, Petra ^LU and Ishiko, J , et al. (2013) In Leukemia 27. p.130-135
- Contribution to journal › Article
Mark Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Hansen, Nils ^LU ; Gordon, Sandra ^LU ; Arvanitakis, Alexandros ^LU ; Rissler, Marianne ^LU ; Juliusson, Gunnar ^LU ; Richter, Johan ^LU ; Järås, Marcus ^LU and Fioretos, Thoas ^LU (2013) In Blood 121(18). p.3709-3713
- Contribution to journal › Article
2010
Mark Molecular and functional studies of ABL1 and FGFR1 fusion oncogenes in myeloproliferative neoplasms
Ågerstam, Helena ^LU (2010) In Lund University Faculty of Medicine Doctoral Dissertation Series 2010:104.
- Thesis › Doctoral thesis (compilation)
Mark Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice
Ågerstam, Helena ^LU ; Järås, Marcus ^LU ; Andersson, Anna ^LU ; Johnels, Petra ^LU ; Hansen, Nils ^LU ; Lassen, Carin ^LU ; Rissler, Marianne ^LU ; Gisselsson Nord, David ^LU ; Olofsson, Tor ^LU and Richter, Johan ^LU , et al. (2010) In Blood 116(12). p.2103-2111
- Contribution to journal › Article
Mark Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
Järås, Marcus ^LU ; Johnels, Petra ^LU ; Hansen, Nils ^LU ; Ågerstam, Helena ^LU ; Tsapogas, Panagiotis ; Rissler, Marianne ^LU ; Lassen, Carin ^LU ; Olofsson, Tor ^LU ; Bjerrum, Ole Weis and Richter, Johan ^LU , et al. (2010) In Proceedings of the National Academy of Sciences 107(37). p.16280-16285
- Contribution to journal › Article