Helena Ågerstam

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2020
Mark Clonal competition within complex evolutionary hierarchies shapes AML over time
Sandén, Carl ^LU ; Lilljebjörn, Henrik ^LU ; Orsmark Pietras, Christina ^LU ; Henningsson, Rasmus ^LU ; Saba, Karim H. ^LU ; Landberg, Niklas ^LU ; Thorsson, Hanna ^LU ; von Palffy, Sofia ^LU ; Peña-Martinez, Pablo ^LU and Högberg, Carl ^LU , et al. (2020) In Nature Communications 11(1).
- Contribution to journal › Article
2019
Mark FLT3 ^N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis
Hyrenius-Wittsten, Axel ^LU ; Pilheden, Mattias ^LU ; Falqués-Costa, Antoni ; Eriksson, Mia ^LU ; Sturesson, Helena ^LU ; Schneider, Pauline ; Wander, Priscilla ; Garcia-Ruiz, Cristian ^LU ; Liu, Jian and Ågerstam, Helena ^LU , et al. (2019) In Leukemia 33(9). p.2310-2314
- Contribution to journal › Letter
2018
Mark CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting
Landberg, Niklas ^LU ; von Palffy, Sofia ^LU ; Askmyr, Maria ^LU ; Lilljebjörn, Henrik ^LU ; Sandén, Carl ^LU ; Rissler, Marianne ^LU ; Mustjoki, Satu ; Hjorth-Hansen, Henrik ; Richter, Johan ^LU and Ågerstam, Helena ^LU , et al. (2018) In Haematologica 103(3). p.447-455
- Contribution to journal › Article
2017
Mark Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib
Landberg, Niklas ^LU ; Dreimane, Arta ; Rissler, Marianne ^LU ; Billström, Rolf and Ågerstam, Helena ^LU (2017) In European Journal of Haematology 99(5). p.442-448
- Contribution to journal › Article
Mark Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells
Askmyr, Maria ^LU ; Von Palffy, Sofia ^LU ; Hansen, Nils ^LU ; Landberg, Niklas ^LU ; Högberg, Carl ^LU ; Rissler, Marianne ^LU ; Ågerstam, Helena ^LU and Fioretos, Thoas ^LU (2017) In PLoS ONE 12(10).
- Contribution to journal › Article
2016
Mark IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
Ågerstam, Helena ^LU ; Hansen, Nils ^LU ; von Palffy, Sofia ^LU ; Sandén, Carl ^LU ; Reckzeh, Kristian ^LU ; Karlsson, Christine ^LU ; Lilljebjörn, Henrik ^LU ; Landberg, Niklas ^LU ; Askmyr, Maria ^LU and Högberg, Carl ^LU , et al. (2016) In Blood 128(23). p.2683-2693
- Contribution to journal › Article
2015
Mark Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Ågerstam, Helena ^LU ; Karlsson, Christine ^LU ; Hansen, Nils ^LU ; Sandén, Carl ^LU ; Askmyr, Maria ^LU ; von Palffy, Sofia ^LU ; Högberg, Carl ^LU ; Rissler, Marianne ^LU ; Wunderlich, Mark and Juliusson, Gunnar ^LU , et al. (2015) In Proceedings of the National Academy of Sciences 112(34). p.10786-10791
- Contribution to journal › Article
Mark IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.
Landberg, Niklas ^LU ; Hansen, Nils ^LU ; Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Lassen, Carin ^LU ; Rissler, Marianne ^LU ; Hansen, H H ; Mustjoki, S ; Järås, Marcus ^LU and Richter, Johan ^LU , et al. (2015) In Leukemia 30(1). p.255-258
- Contribution to journal › Article
2014
Mark Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.
Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Lilljebjörn, Henrik ^LU ; Hansen, Nils ^LU ; Karlsson, Christine ^LU ; von Palffy, Sofia ^LU ; Landberg, Niklas ^LU ; Högberg, Carl ^LU ; Lassen, Carin ^LU and Rissler, Marianne ^LU , et al. (2014) In Blood Cancer Journal 4.
- Contribution to journal › Article
Mark RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib.
Lilljebjörn, Henrik ^LU ; Ågerstam, Helena ^LU ; Orsmark Pietras, Christina ^LU ; Rissler, Marianne ^LU ; Ehrencrona, Hans ^LU ; Nilsson, L ; Richter, Johan ^LU and Fioretos, Thoas ^LU (2014) In Leukemia 28(4). p.977-979
- Contribution to journal › Letter

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