Bioengineering Approaches for the Distal Lung
Wagner, Darcy E. LU
(2021)
1.
p.788-795
- Abstract
Chronic and acute lung diseases are the third and fourth leading causes of global mortality. Distal lung tissue is severely damaged in many lung diseases, causing respiratory insufficiency from loss of surface area available for gas exchange. Current therapies aim at relieving symptoms and are unable to reverse disease. Lung transplantation remains the only potential curative option at end-stage disease but is severely limited by a lack of suitable donor lungs and low long-term survival. Bioengineering lung tissue or bioengineering cells with biomaterials for transplantation is an exciting new approach to (re)generate tissue to close this large unmet clinical need.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/02773e02-9be7-4dc0-933b-73b3704f98b1
- author
- Wagner, Darcy E.
LU
- organization
- publishing date
- 2021
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- 3D bioprinting, Alveolar, Bioengineering, Bioreactor, Chronic lung disease, Chronic obstructive pulmonary disease, Decellularization, Extracellular matrix, Pulmonary fibrosis, Pulmonary hypertension, Scaffold, Small airways, Synthetic scaffold
- host publication
- Encyclopedia of Respiratory Medicine, Second Edition
- volume
- 1
- pages
- 8 pages
- publisher
- ScienceDirect, Elsevier
- external identifiers
-
- scopus:85143101988
- ISBN
- 9780081027240
- 9780081027233
- DOI
- 10.1016/B978-0-08-102723-3.00264-X
- language
- English
- LU publication?
- yes
- id
- 02773e02-9be7-4dc0-933b-73b3704f98b1
- date added to LUP
- 2023-02-07 15:53:20
- date last changed
- 2024-05-30 22:56:57
@inbook{02773e02-9be7-4dc0-933b-73b3704f98b1,
abstract = {{<p>Chronic and acute lung diseases are the third and fourth leading causes of global mortality. Distal lung tissue is severely damaged in many lung diseases, causing respiratory insufficiency from loss of surface area available for gas exchange. Current therapies aim at relieving symptoms and are unable to reverse disease. Lung transplantation remains the only potential curative option at end-stage disease but is severely limited by a lack of suitable donor lungs and low long-term survival. Bioengineering lung tissue or bioengineering cells with biomaterials for transplantation is an exciting new approach to (re)generate tissue to close this large unmet clinical need.</p>}},
author = {{Wagner, Darcy E.}},
booktitle = {{Encyclopedia of Respiratory Medicine, Second Edition}},
isbn = {{9780081027240}},
keywords = {{3D bioprinting; Alveolar; Bioengineering; Bioreactor; Chronic lung disease; Chronic obstructive pulmonary disease; Decellularization; Extracellular matrix; Pulmonary fibrosis; Pulmonary hypertension; Scaffold; Small airways; Synthetic scaffold}},
language = {{eng}},
pages = {{788--795}},
publisher = {{ScienceDirect, Elsevier}},
title = {{Bioengineering Approaches for the Distal Lung}},
url = {{http://dx.doi.org/10.1016/B978-0-08-102723-3.00264-X}},
doi = {{10.1016/B978-0-08-102723-3.00264-X}},
volume = {{1}},
year = {{2021}},
}