Sensors of Succinate : Neural Stem Cell Grafts Fight Neuroinflammation
Kokaia, Zaal LU
and Lindvall, Olle
LU
(2018)
In Cell Stem Cell
22(3).
p.283-285
- Abstract
In this issue of Cell Stem Cell, Peruzzotti-Jametti et al. (2018) demonstrate how neural stem cells, transplanted in a mouse model of multiple sclerosis, respond to extracellular succinate and modulate neuroinflammation by releasing anti-inflammatory prostaglandin E2 and scavenging succinate. This mechanism reduces CNS damage and ameliorates motor impairment. In this issue of Cell Stem Cell, Peruzzotti-Jametti et al. (2018) demonstrate how neural stem cells, transplanted in a mouse model of multiple sclerosis, respond to extracellular succinate and modulate neuroinflammation by releasing anti-inflammatory prostaglandin E2 and scavenging succinate. This mechanism reduces CNS damage and ameliorates motor impairment.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/031deacb-b2b7-4626-a71e-f4ccaf7cfee6
- author
- Kokaia, Zaal
LU
and Lindvall, Olle
LU
- organization
- publishing date
- 2018-03-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cell Stem Cell
- volume
- 22
- issue
- 3
- pages
- 3 pages
- publisher
- Cell Press
- external identifiers
-
- pmid:29499143
- scopus:85042587421
- ISSN
- 1934-5909
- DOI
- 10.1016/j.stem.2018.01.019
- language
- English
- LU publication?
- yes
- id
- 031deacb-b2b7-4626-a71e-f4ccaf7cfee6
- date added to LUP
- 2018-03-08 10:24:13
- date last changed
- 2024-10-14 23:01:26
@article{031deacb-b2b7-4626-a71e-f4ccaf7cfee6,
abstract = {{<p>In this issue of Cell Stem Cell, Peruzzotti-Jametti et al. (2018) demonstrate how neural stem cells, transplanted in a mouse model of multiple sclerosis, respond to extracellular succinate and modulate neuroinflammation by releasing anti-inflammatory prostaglandin E2 and scavenging succinate. This mechanism reduces CNS damage and ameliorates motor impairment. In this issue of Cell Stem Cell, Peruzzotti-Jametti et al. (2018) demonstrate how neural stem cells, transplanted in a mouse model of multiple sclerosis, respond to extracellular succinate and modulate neuroinflammation by releasing anti-inflammatory prostaglandin E2 and scavenging succinate. This mechanism reduces CNS damage and ameliorates motor impairment.</p>}},
author = {{Kokaia, Zaal and Lindvall, Olle}},
issn = {{1934-5909}},
language = {{eng}},
month = {{03}},
number = {{3}},
pages = {{283--285}},
publisher = {{Cell Press}},
series = {{Cell Stem Cell}},
title = {{Sensors of Succinate : Neural Stem Cell Grafts Fight Neuroinflammation}},
url = {{http://dx.doi.org/10.1016/j.stem.2018.01.019}},
doi = {{10.1016/j.stem.2018.01.019}},
volume = {{22}},
year = {{2018}},
}