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First clinical experience of a ring-configured cadmium zinc telluride camera : A comparative study versus conventional gamma camera systems

Cerić Andelius, Irma LU ; Minarik, David LU ; Persson, Eva LU ; Mosén, Henrik LU ; Valind, Kristian LU orcid ; Trägårdh, Elin LU and Oddstig, Jenny LU (2024) In Clinical Physiology and Functional Imaging 44(1). p.79-88
Abstract

BACKGROUND: A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process.

METHOD: Seventy-six patients (bone-, cardiac- and lung scan) were scanned on a conventional gamma camera (planar and/or single-photon emission computed tomography [SPECT]/SPECT-CT) used in clinical routine and on the ring-configurated CZT camera Starguide (GE Healthcare). These data were used to validate and optimize the Starguide system for routine clinical use.

RESULTS:... (More)

BACKGROUND: A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process.

METHOD: Seventy-six patients (bone-, cardiac- and lung scan) were scanned on a conventional gamma camera (planar and/or single-photon emission computed tomography [SPECT]/SPECT-CT) used in clinical routine and on the ring-configurated CZT camera Starguide (GE Healthcare). These data were used to validate and optimize the Starguide system for routine clinical use.

RESULTS: Comparable image quality for the Starguide system, to that of the conventional gamma camera, was achieved for bone scan (4 min/bed position [BP] using a relative difference prior [RDP] with gamma 2 and beta 0.4, along with 10 iterations and 10 subsets), cardiac scan (8 min [stress] and 3 min 20 s [rest] using median root prior [MRP] with beta 0.07 non attenuation corrected and 0.008 attenuation corrected and 50 interations and 10 subsets for both stress and rest) and lung scan (10 min [vent] and 5 min [perf] using RDP with gamma 0.5 and beta 0.03 [vent] and 0.02 [perf] and 20 interations and 10 subsets for both vent and perf).

CONCLUSIONS: It was possible to transition from a conventional gamma camera to the Starguide system as part of the clinical routine, with acceptable image quality. Images from the Starguide system were deemed to be at least as good as those from a conventional gamma camera.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Physiology and Functional Imaging
volume
44
issue
1
pages
10 pages
publisher
John Wiley & Sons Inc.
external identifiers
  • scopus:85168619619
  • pmid:37592454
ISSN
1475-0961
DOI
10.1111/cpf.12853
project
SPECT-CT with new gamma camera technique and new reconstruction algorithms
language
English
LU publication?
yes
additional info
© 2023 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of Scandinavian Society of Clinical Physiology and Nuclear Medicine.
id
03456e6d-0eaf-410d-a164-889b91642595
date added to LUP
2023-08-24 21:22:07
date last changed
2024-04-19 00:50:00
@article{03456e6d-0eaf-410d-a164-889b91642595,
  abstract     = {{<p>BACKGROUND: A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process.</p><p>METHOD: Seventy-six patients (bone-, cardiac- and lung scan) were scanned on a conventional gamma camera (planar and/or single-photon emission computed tomography [SPECT]/SPECT-CT) used in clinical routine and on the ring-configurated CZT camera Starguide (GE Healthcare). These data were used to validate and optimize the Starguide system for routine clinical use.</p><p>RESULTS: Comparable image quality for the Starguide system, to that of the conventional gamma camera, was achieved for bone scan (4 min/bed position [BP] using a relative difference prior [RDP] with gamma 2 and beta 0.4, along with 10 iterations and 10 subsets), cardiac scan (8 min [stress] and 3 min 20 s [rest] using median root prior [MRP] with beta 0.07 non attenuation corrected and 0.008 attenuation corrected and 50 interations and 10 subsets for both stress and rest) and lung scan (10 min [vent] and 5 min [perf] using RDP with gamma 0.5 and beta 0.03 [vent] and 0.02 [perf] and 20 interations and 10 subsets for both vent and perf).</p><p>CONCLUSIONS: It was possible to transition from a conventional gamma camera to the Starguide system as part of the clinical routine, with acceptable image quality. Images from the Starguide system were deemed to be at least as good as those from a conventional gamma camera.</p>}},
  author       = {{Cerić Andelius, Irma and Minarik, David and Persson, Eva and Mosén, Henrik and Valind, Kristian and Trägårdh, Elin and Oddstig, Jenny}},
  issn         = {{1475-0961}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{79--88}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Clinical Physiology and Functional Imaging}},
  title        = {{First clinical experience of a ring-configured cadmium zinc telluride camera : A comparative study versus conventional gamma camera systems}},
  url          = {{http://dx.doi.org/10.1111/cpf.12853}},
  doi          = {{10.1111/cpf.12853}},
  volume       = {{44}},
  year         = {{2024}},
}