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Long-term outcomes following adolescent metabolic and bariatric surgery

Beamish, Andrew ; Ryan Harper, Elizabeth ; Järvholm, Kajsa LU ; Janson, Annika and Olbers, Torsten (2023) In The Journal of clinical endocrinology and metabolism 108(9). p.2184-2192
Abstract
Severe obesity in adolescence negatively impacts upon health and wellbeing. Lifestyle modifications do not usually achieve a sufficient degree or durability of weight loss to mitigate the risk of medical complications. In recent years, metabolic and bariatric surgery (MBS), already a well-established treatment for adults with severe obesity, has emerged as an option in adolescents. Controlled studies in this age group have demonstrated substantial and sustained weight loss, improvements in associated health parameters, and a safety profile surpassing that observed in adult patients. This review aims to present published data on the results of MBS in adolescents with a focus on long-term outcomes. Indications for bariatric surgery and... (More)
Severe obesity in adolescence negatively impacts upon health and wellbeing. Lifestyle modifications do not usually achieve a sufficient degree or durability of weight loss to mitigate the risk of medical complications. In recent years, metabolic and bariatric surgery (MBS), already a well-established treatment for adults with severe obesity, has emerged as an option in adolescents. Controlled studies in this age group have demonstrated substantial and sustained weight loss, improvements in associated health parameters, and a safety profile surpassing that observed in adult patients. This review aims to present published data on the results of MBS in adolescents with a focus on long-term outcomes. Indications for bariatric surgery and aspects of timing in the young person's life are also presented, along with safety considerations and factors influencing patient selection for surgery. We conclude, predominantly from short- to medium-term outcomes data, that MBS is a safe and valuable therapeutic option for adolescents with severe obesity. Considering the poor health and social wellbeing prognosis in this group, MBS appears to be underutilized. The need for continued research, multiprofessional specialist provision, coherent contemporary clinical guidelines, and routine long-term follow-up in adolescents undergoing MBS is highlighted. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Journal of clinical endocrinology and metabolism
volume
108
issue
9
pages
2184 - 2192
publisher
Oxford University Press
external identifiers
  • pmid:36947630
  • scopus:85168315872
ISSN
1945-7197
DOI
10.1210/clinem/dgad155
language
English
LU publication?
yes
id
042cf91e-53f6-464d-a902-61750eeedfe7
date added to LUP
2023-03-24 09:22:35
date last changed
2024-02-20 00:33:32
@article{042cf91e-53f6-464d-a902-61750eeedfe7,
  abstract     = {{Severe obesity in adolescence negatively impacts upon health and wellbeing. Lifestyle modifications do not usually achieve a sufficient degree or durability of weight loss to mitigate the risk of medical complications. In recent years, metabolic and bariatric surgery (MBS), already a well-established treatment for adults with severe obesity, has emerged as an option in adolescents. Controlled studies in this age group have demonstrated substantial and sustained weight loss, improvements in associated health parameters, and a safety profile surpassing that observed in adult patients. This review aims to present published data on the results of MBS in adolescents with a focus on long-term outcomes. Indications for bariatric surgery and aspects of timing in the young person's life are also presented, along with safety considerations and factors influencing patient selection for surgery. We conclude, predominantly from short- to medium-term outcomes data, that MBS is a safe and valuable therapeutic option for adolescents with severe obesity. Considering the poor health and social wellbeing prognosis in this group, MBS appears to be underutilized. The need for continued research, multiprofessional specialist provision, coherent contemporary clinical guidelines, and routine long-term follow-up in adolescents undergoing MBS is highlighted.}},
  author       = {{Beamish, Andrew and Ryan Harper, Elizabeth and Järvholm, Kajsa and Janson, Annika and Olbers, Torsten}},
  issn         = {{1945-7197}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{2184--2192}},
  publisher    = {{Oxford University Press}},
  series       = {{The Journal of clinical endocrinology and metabolism}},
  title        = {{Long-term outcomes following adolescent metabolic and bariatric surgery}},
  url          = {{http://dx.doi.org/10.1210/clinem/dgad155}},
  doi          = {{10.1210/clinem/dgad155}},
  volume       = {{108}},
  year         = {{2023}},
}