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Proton magnetic resonance relaxation times T1 and T2 related to postmortem interval : An Investigation on Porcine Brain Tissue

Györffy-Wagner, Z. ; Englund, E. LU orcid ; Larsson, E. M. LU ; Brun, A. LU ; Cronqvist, S. and Persson, B. LU orcid (1986) In Acta Radiologica 27(1). p.115-118
Abstract

In order to establish the validity of in vitro determination of the proton magnetic resonance (MR) relaxation times T1 and T2 in brain tissue at increasing time delay after death or operative excision, 81 brain tissue samples from 23 pigs were analyzed repeatedly. These samples, representing cortex, caudate nucleus and white matter, were studied microscopically after MR measurements. The T1 values exhibited no time dependence and the T2 values decreased slightly during the interval 2 to 90 hours after death. The samples were stored at +8°C between the measurements. These results indicate that reliable in vitro measurements can be obtained in autopsy or surgical brain tissue specimens within 90 hours after death or excision, if handled... (More)

In order to establish the validity of in vitro determination of the proton magnetic resonance (MR) relaxation times T1 and T2 in brain tissue at increasing time delay after death or operative excision, 81 brain tissue samples from 23 pigs were analyzed repeatedly. These samples, representing cortex, caudate nucleus and white matter, were studied microscopically after MR measurements. The T1 values exhibited no time dependence and the T2 values decreased slightly during the interval 2 to 90 hours after death. The samples were stored at +8°C between the measurements. These results indicate that reliable in vitro measurements can be obtained in autopsy or surgical brain tissue specimens within 90 hours after death or excision, if handled properly.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
keywords
Magnetic resonance, tissue characterization
in
Acta Radiologica
volume
27
issue
1
pages
4 pages
publisher
SAGE Publications
external identifiers
  • pmid:3962713
  • scopus:0022598099
ISSN
0284-1851
DOI
10.1177/028418518602700123
language
English
LU publication?
yes
id
045cef69-74e1-4957-8950-79a470fd7c6b
date added to LUP
2020-05-07 21:19:31
date last changed
2024-01-02 10:38:45
@article{045cef69-74e1-4957-8950-79a470fd7c6b,
  abstract     = {{<p>In order to establish the validity of in vitro determination of the proton magnetic resonance (MR) relaxation times T1 and T2 in brain tissue at increasing time delay after death or operative excision, 81 brain tissue samples from 23 pigs were analyzed repeatedly. These samples, representing cortex, caudate nucleus and white matter, were studied microscopically after MR measurements. The T1 values exhibited no time dependence and the T2 values decreased slightly during the interval 2 to 90 hours after death. The samples were stored at +8°C between the measurements. These results indicate that reliable in vitro measurements can be obtained in autopsy or surgical brain tissue specimens within 90 hours after death or excision, if handled properly.</p>}},
  author       = {{Györffy-Wagner, Z. and Englund, E. and Larsson, E. M. and Brun, A. and Cronqvist, S. and Persson, B.}},
  issn         = {{0284-1851}},
  keywords     = {{Magnetic resonance; tissue characterization}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1}},
  pages        = {{115--118}},
  publisher    = {{SAGE Publications}},
  series       = {{Acta Radiologica}},
  title        = {{Proton magnetic resonance relaxation times T1 and T2 related to postmortem interval : An Investigation on Porcine Brain Tissue}},
  url          = {{http://dx.doi.org/10.1177/028418518602700123}},
  doi          = {{10.1177/028418518602700123}},
  volume       = {{27}},
  year         = {{1986}},
}