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Osteoporotic fractures among foreign-born individuals : a national Swedish study

Wändell, P. LU ; Li, X. LU ; Carlsson, A. C. ; Sundquist, J. LU and Sundquist, K. LU (2020) In Osteoporosis International
Abstract

Summary: In this national study of osteoporotic fractures in foreign-born individuals, we found a lower risk of osteoporotic fractures in general among foreign-born individuals compared with Swedish-born, especially in immigrants from southern Europe. A higher risk was found among some groups, i.e. men and women from Bosnia and Iraq and men from Lebanon. Introduction: The aim of this study was to analyse risk of osteoporotic fractures in foreign-born individuals compared with Swedish-born individuals. Methods: This was a nationwide study of individuals 50 years of age and older (N = 2,775,736). Osteoporotic fractures were defined as at least one registered diagnosis of fractures in the hip, humerus, forearm or vertebrae, in the National... (More)

Summary: In this national study of osteoporotic fractures in foreign-born individuals, we found a lower risk of osteoporotic fractures in general among foreign-born individuals compared with Swedish-born, especially in immigrants from southern Europe. A higher risk was found among some groups, i.e. men and women from Bosnia and Iraq and men from Lebanon. Introduction: The aim of this study was to analyse risk of osteoporotic fractures in foreign-born individuals compared with Swedish-born individuals. Methods: This was a nationwide study of individuals 50 years of age and older (N = 2,775,736). Osteoporotic fractures were defined as at least one registered diagnosis of fractures in the hip, humerus, forearm or vertebrae, in the National Patient Register between January 1, 1998, and December 31, 2012. Cox regression analysis was used to estimate the relative risk (hazard ratios (HR) with 99% confidence intervals (CI)) of incident osteoporotic fractures in foreign-born compared with Swedish-born individuals. The Cox regression models were stratified by sex and adjusted for age, comorbidities and sociodemographic status. Results: A total of 362,899 osteoporotic fractures were registered (96,847 among men and 266,052 among women), with hip fractures dominating (54.0% among men, 42.6% among women). Fully adjusted HRs (99% CI) were for all immigrant men 0.75 (99% CI, 0.73–0.78) and women 0.83 (99% CI, 0.81–0.84), with significantly lower HRs among most groups but with higher HRs in certain countries. For the specific fractures, higher HRs were found for lower forearm fractures for men from Asia and for vertebral fractures among women from Asia. Conclusions: We observed a generally lower risk of osteoporotic fractures among first-generation immigrants, with few exceptions.

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organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Forearm fractures, Gender, Hip fractures, Humerus fractures, Immigrants, Neighbourhood, Osteoporotic fractures, Socioeconomic status, Vertebral fractures
in
Osteoporosis International
publisher
Springer
external identifiers
  • pmid:32814995
  • scopus:85089574017
ISSN
0937-941X
DOI
10.1007/s00198-020-05597-5
language
English
LU publication?
yes
id
0499ef77-852d-4a0f-b571-75dc3edac4a1
date added to LUP
2020-08-28 12:34:23
date last changed
2020-09-02 05:04:16
@article{0499ef77-852d-4a0f-b571-75dc3edac4a1,
  abstract     = {<p>Summary: In this national study of osteoporotic fractures in foreign-born individuals, we found a lower risk of osteoporotic fractures in general among foreign-born individuals compared with Swedish-born, especially in immigrants from southern Europe. A higher risk was found among some groups, i.e. men and women from Bosnia and Iraq and men from Lebanon. Introduction: The aim of this study was to analyse risk of osteoporotic fractures in foreign-born individuals compared with Swedish-born individuals. Methods: This was a nationwide study of individuals 50 years of age and older (N = 2,775,736). Osteoporotic fractures were defined as at least one registered diagnosis of fractures in the hip, humerus, forearm or vertebrae, in the National Patient Register between January 1, 1998, and December 31, 2012. Cox regression analysis was used to estimate the relative risk (hazard ratios (HR) with 99% confidence intervals (CI)) of incident osteoporotic fractures in foreign-born compared with Swedish-born individuals. The Cox regression models were stratified by sex and adjusted for age, comorbidities and sociodemographic status. Results: A total of 362,899 osteoporotic fractures were registered (96,847 among men and 266,052 among women), with hip fractures dominating (54.0% among men, 42.6% among women). Fully adjusted HRs (99% CI) were for all immigrant men 0.75 (99% CI, 0.73–0.78) and women 0.83 (99% CI, 0.81–0.84), with significantly lower HRs among most groups but with higher HRs in certain countries. For the specific fractures, higher HRs were found for lower forearm fractures for men from Asia and for vertebral fractures among women from Asia. Conclusions: We observed a generally lower risk of osteoporotic fractures among first-generation immigrants, with few exceptions.</p>},
  author       = {Wändell, P. and Li, X. and Carlsson, A. C. and Sundquist, J. and Sundquist, K.},
  issn         = {0937-941X},
  language     = {eng},
  month        = {08},
  publisher    = {Springer},
  series       = {Osteoporosis International},
  title        = {Osteoporotic fractures among foreign-born individuals : a national Swedish study},
  url          = {http://dx.doi.org/10.1007/s00198-020-05597-5},
  doi          = {10.1007/s00198-020-05597-5},
  year         = {2020},
}