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Changes in alcohol consumption after treatment for depression : A secondary analysis of the Swedish randomised controlled study REGASSA

Strid, Catharina LU ; Hallgren, Mats ; Forsell, Yvonne ; Kraepelien, Martin and Öjehagen, Agneta LU (2019) In BMJ Open 9(11).
Abstract

Objectives Mental health problems and hazardous alcohol consumption often co-exist. Hazardous drinking could have a negative impact on different aspects of health and also negatively influence the effect of mental health treatment. The aims of this study were to examine if alcohol consumption patterns changed after treatment for depression and if the changes differed by treatment arm and patient sex. Methods This study of 540 participants was conducted in a large randomised controlled trial (RCT) that aimed to compare the effect of internet-based cognitive behavioural therapy, physical exercise and treatment as usual on 945 participants with mild-to-moderate depression. Treatment lasted for 12 weeks; alcohol consumption (Alcohol Use... (More)

Objectives Mental health problems and hazardous alcohol consumption often co-exist. Hazardous drinking could have a negative impact on different aspects of health and also negatively influence the effect of mental health treatment. The aims of this study were to examine if alcohol consumption patterns changed after treatment for depression and if the changes differed by treatment arm and patient sex. Methods This study of 540 participants was conducted in a large randomised controlled trial (RCT) that aimed to compare the effect of internet-based cognitive behavioural therapy, physical exercise and treatment as usual on 945 participants with mild-to-moderate depression. Treatment lasted for 12 weeks; alcohol consumption (Alcohol Use Disorder Identification Test (AUDIT)) and depression (Montgomery Åsberg Depression Rating Scale (MADRS)) were assessed at baseline and 12-month follow-up. Changes in alcohol consumption were examined in relation to depression severity, treatment arm and patient sex. Results The AUDIT distribution for the entire group remained unchanged after treatment for depression. Hazardous drinkers exhibit decreases in AUDIT scores, although they remained hazardous drinkers according to the cut-off scores. Hazardous drinkers experienced similar improvements in symptoms of depression compared with non-hazardous drinkers, and there was no significant relation between changes in AUDIT score and changes in depression. No differences between treatment arm and patient sex were found. Conclusion The alcohol consumption did not change, despite treatment effects on depression. Patients with depression should be screened for hazardous drinking habits and offered evidence-based treatment for hazardous alcohol use where this is indicated. Trial registration number DRKS00008745.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
depression & mood disorders, primary care, substance misuse
in
BMJ Open
volume
9
issue
11
article number
e028236
publisher
BMJ Publishing Group
external identifiers
  • pmid:31712330
  • scopus:85074851745
ISSN
2044-6055
DOI
10.1136/bmjopen-2018-028236
language
English
LU publication?
yes
id
049f8e6c-f5d7-4f26-b097-17c777668430
date added to LUP
2019-11-29 13:56:33
date last changed
2024-05-29 04:22:48
@article{049f8e6c-f5d7-4f26-b097-17c777668430,
  abstract     = {{<p>Objectives Mental health problems and hazardous alcohol consumption often co-exist. Hazardous drinking could have a negative impact on different aspects of health and also negatively influence the effect of mental health treatment. The aims of this study were to examine if alcohol consumption patterns changed after treatment for depression and if the changes differed by treatment arm and patient sex. Methods This study of 540 participants was conducted in a large randomised controlled trial (RCT) that aimed to compare the effect of internet-based cognitive behavioural therapy, physical exercise and treatment as usual on 945 participants with mild-to-moderate depression. Treatment lasted for 12 weeks; alcohol consumption (Alcohol Use Disorder Identification Test (AUDIT)) and depression (Montgomery Åsberg Depression Rating Scale (MADRS)) were assessed at baseline and 12-month follow-up. Changes in alcohol consumption were examined in relation to depression severity, treatment arm and patient sex. Results The AUDIT distribution for the entire group remained unchanged after treatment for depression. Hazardous drinkers exhibit decreases in AUDIT scores, although they remained hazardous drinkers according to the cut-off scores. Hazardous drinkers experienced similar improvements in symptoms of depression compared with non-hazardous drinkers, and there was no significant relation between changes in AUDIT score and changes in depression. No differences between treatment arm and patient sex were found. Conclusion The alcohol consumption did not change, despite treatment effects on depression. Patients with depression should be screened for hazardous drinking habits and offered evidence-based treatment for hazardous alcohol use where this is indicated. Trial registration number DRKS00008745.</p>}},
  author       = {{Strid, Catharina and Hallgren, Mats and Forsell, Yvonne and Kraepelien, Martin and Öjehagen, Agneta}},
  issn         = {{2044-6055}},
  keywords     = {{depression & mood disorders; primary care; substance misuse}},
  language     = {{eng}},
  number       = {{11}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{BMJ Open}},
  title        = {{Changes in alcohol consumption after treatment for depression : A secondary analysis of the Swedish randomised controlled study REGASSA}},
  url          = {{http://dx.doi.org/10.1136/bmjopen-2018-028236}},
  doi          = {{10.1136/bmjopen-2018-028236}},
  volume       = {{9}},
  year         = {{2019}},
}