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Cryptorchidism in Sweden : A Nationwide Study of Prevalence, Operative Management, and Complications

Bergbrant, Susanna; Omling, Erik LU ; Björk, Jonas and Hagander, Lars LU (2018) In Journal of Pediatrics
Abstract

Objectives: To review the cumulative prevalence, operative management, and complications of treatment for cryptorchidism in Sweden. Study design: A nationwide observational study from longitudinal register data of all Swedish-born boys 0-18 years of age, diagnosed with cryptorchidism from 2001 to 2014. Primary outcomes were occurrence and age at primary surgery. Secondary outcomes included type of procedure and surgical site infection. Results: Of 20 375 boys diagnosed with cryptorchidism in 2001-2014, 12 766 were surgically treated. The cumulative childhood prevalence was 1.8% (95% CI, 1.5-2.0), with a higher prevalence in boys born prematurely, small for gestational age, or with low birth weight. The median age at treatment decreased... (More)

Objectives: To review the cumulative prevalence, operative management, and complications of treatment for cryptorchidism in Sweden. Study design: A nationwide observational study from longitudinal register data of all Swedish-born boys 0-18 years of age, diagnosed with cryptorchidism from 2001 to 2014. Primary outcomes were occurrence and age at primary surgery. Secondary outcomes included type of procedure and surgical site infection. Results: Of 20 375 boys diagnosed with cryptorchidism in 2001-2014, 12 766 were surgically treated. The cumulative childhood prevalence was 1.8% (95% CI, 1.5-2.0), with a higher prevalence in boys born prematurely, small for gestational age, or with low birth weight. The median age at treatment decreased from 6.2 years in 2001 to 3.4 years in 2014 (P < .001). Still, 94.1% (95% CI, 92.7-95.6) had surgery after the recommended 1 year of age in 2014. Variations in age at surgery between Swedish counties were great (range, 2.9-5.9 years of age). There were no deaths within 30 days after surgery and the frequency of surgical site infection was low (1.4%; 95% CI, 1.1-1.6). Conclusions: The cumulative childhood prevalence of cryptorchidism was high, and complications were rare. Few boys underwent surgery in a timely manner according to clinical guidelines, and standards of care varied considerably across the country. Further research and collective actions are needed to improve the detection and management of congenital cryptorchidism.

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author
organization
publishing date
type
Contribution to journal
publication status
in press
subject
keywords
Cryptorchidism, Epidemiology, Surgery
in
Journal of Pediatrics
publisher
Academic Press
external identifiers
  • scopus:85040372156
ISSN
0022-3476
DOI
10.1016/j.jpeds.2017.09.062
language
English
LU publication?
yes
id
06965884-bf3d-452c-8bf3-339d02a42453
date added to LUP
2018-02-23 19:30:45
date last changed
2018-05-13 04:38:47
@article{06965884-bf3d-452c-8bf3-339d02a42453,
  abstract     = {<p>Objectives: To review the cumulative prevalence, operative management, and complications of treatment for cryptorchidism in Sweden. Study design: A nationwide observational study from longitudinal register data of all Swedish-born boys 0-18 years of age, diagnosed with cryptorchidism from 2001 to 2014. Primary outcomes were occurrence and age at primary surgery. Secondary outcomes included type of procedure and surgical site infection. Results: Of 20 375 boys diagnosed with cryptorchidism in 2001-2014, 12 766 were surgically treated. The cumulative childhood prevalence was 1.8% (95% CI, 1.5-2.0), with a higher prevalence in boys born prematurely, small for gestational age, or with low birth weight. The median age at treatment decreased from 6.2 years in 2001 to 3.4 years in 2014 (P &lt; .001). Still, 94.1% (95% CI, 92.7-95.6) had surgery after the recommended 1 year of age in 2014. Variations in age at surgery between Swedish counties were great (range, 2.9-5.9 years of age). There were no deaths within 30 days after surgery and the frequency of surgical site infection was low (1.4%; 95% CI, 1.1-1.6). Conclusions: The cumulative childhood prevalence of cryptorchidism was high, and complications were rare. Few boys underwent surgery in a timely manner according to clinical guidelines, and standards of care varied considerably across the country. Further research and collective actions are needed to improve the detection and management of congenital cryptorchidism.</p>},
  author       = {Bergbrant, Susanna and Omling, Erik and Björk, Jonas and Hagander, Lars},
  issn         = {0022-3476},
  keyword      = {Cryptorchidism,Epidemiology,Surgery},
  language     = {eng},
  publisher    = {Academic Press},
  series       = {Journal of Pediatrics},
  title        = {Cryptorchidism in Sweden : A Nationwide Study of Prevalence, Operative Management, and Complications},
  url          = {http://dx.doi.org/10.1016/j.jpeds.2017.09.062},
  year         = {2018},
}