Improved acoustophoretic circulating tumor cell (CTC) separation for low target cell numbers in clinical volumes
Lenshof, A. LU
; Magnusson, Cecilia
LU
; Augustsson, P.
LU
; Haflidadottir, B.
LU
; Lilja, H.
LU
and Laurell, T.
LU
(2014)
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
p.594-596
- Abstract
We present an improved acoustophoretic system for circulating tumor cell separation from blood. The system is operated by pressure driven flow, including flow sensors and a feed-back loop for precise flow control. The pressure driven system provides a user interface that can be handled by a non-skilled operator, and most importantly full clinical samples of 7 mL can be processed in 70 minutes. The improved flow control enables recovery of rare tumor cell populations ≈10 cells/mL spiked in whole blood at a recovery close to 100%.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/07508598-3cb8-4425-a1d3-a03ecb775584
- author
- Lenshof, A.
LU
; Magnusson, Cecilia
LU
; Augustsson, P.
LU
; Haflidadottir, B.
LU
; Lilja, H.
LU
and Laurell, T.
LU
- organization
-
- MultiPark: Multidisciplinary research focused on Parkinson´s disease
- Acoustofluidics group (research group)
- Clinical Chemistry, Malmö (research group)
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- Department of Biomedical Engineering
- EpiHealth: Epidemiology for Health
- publishing date
- 2014
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Acoustophoresis, Cancer, Circulation tumor cells, Rare cell, Separation
- host publication
- 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
- series title
- 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
- pages
- 594 - 596
- publisher
- Chemical and Biological Microsystems Society
- conference name
- 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
- conference location
- San Antonio, United States
- conference dates
- 2014-10-26 - 2014-10-30
- external identifiers
-
- scopus:84941687206
- ISBN
- 9780979806476
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 14CBMS.
- id
- 07508598-3cb8-4425-a1d3-a03ecb775584
- date added to LUP
- 2023-02-10 11:14:40
- date last changed
- 2024-10-03 17:06:09
@inproceedings{07508598-3cb8-4425-a1d3-a03ecb775584,
abstract = {{<p>We present an improved acoustophoretic system for circulating tumor cell separation from blood. The system is operated by pressure driven flow, including flow sensors and a feed-back loop for precise flow control. The pressure driven system provides a user interface that can be handled by a non-skilled operator, and most importantly full clinical samples of 7 mL can be processed in 70 minutes. The improved flow control enables recovery of rare tumor cell populations ≈10 cells/mL spiked in whole blood at a recovery close to 100%.</p>}},
author = {{Lenshof, A. and Magnusson, Cecilia and Augustsson, P. and Haflidadottir, B. and Lilja, H. and Laurell, T.}},
booktitle = {{18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014}},
isbn = {{9780979806476}},
keywords = {{Acoustophoresis; Cancer; Circulation tumor cells; Rare cell; Separation}},
language = {{eng}},
pages = {{594--596}},
publisher = {{Chemical and Biological Microsystems Society}},
series = {{18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014}},
title = {{Improved acoustophoretic circulating tumor cell (CTC) separation for low target cell numbers in clinical volumes}},
year = {{2014}},
}