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Trends in kidney transplantation rate across Europe : a study from the ERA Registry

Boenink, Rianne ; Kramer, Anneke ; Tuinhout, Rosalie E. ; Savoye, Emilie ; Åsberg, Anders ; Idrizi, Alma ; Kerschbaum, Julia ; Ziedina, Ieva ; Ziginskiene, Edita and Farrugia, Emanuel , et al. (2023) In Nephrology Dialysis Transplantation 38(6). p.1528-1539
Abstract

Background. The aim of this study was to identify trends in total, deceased donor (DD) and living donor (LD) kidney transplantation (KT) rates in European countries. Methods. The European Renal Association (ERA) Registry and the Global Observatory on Donation and Transplantation (GODT) databases were used to obtain the number of KTs in individual European countries between 2010 and 2018. General population counts were obtained from Eurostat or the national bureaus of statistics. The KT rate per million population (p.m.p.) and the average annual percentage change (APC) were calculated. Results. The total KT rate in the 40 participating countries increased with 1.9% annually [95% confidence interval (CI) 1.5, 2.2] from 29.6 p.m.p. in 2010... (More)

Background. The aim of this study was to identify trends in total, deceased donor (DD) and living donor (LD) kidney transplantation (KT) rates in European countries. Methods. The European Renal Association (ERA) Registry and the Global Observatory on Donation and Transplantation (GODT) databases were used to obtain the number of KTs in individual European countries between 2010 and 2018. General population counts were obtained from Eurostat or the national bureaus of statistics. The KT rate per million population (p.m.p.) and the average annual percentage change (APC) were calculated. Results. The total KT rate in the 40 participating countries increased with 1.9% annually [95% confidence interval (CI) 1.5, 2.2] from 29.6 p.m.p. in 2010 to 34.7 p.m.p. in 2018, reflecting an increase of 3.4 p.m.p. in the DD-KT rate (from 21.6 p.m.p. to 25.0 p.m.p.; APC 1.9%; 95% CI 1.3, 2.4) and of 1.5 p.m.p. in the LD-KT rate (from 8.1 p.m.p. to 9.6 p.m.p.; APC 1.6%; 95% CI 1.0, 2.3). The trends in KT rate varied widely across European countries. An East-West gradient was observed for DD-KT rate, with Western European countries performing more KTs. In addition, most countries performed fewer LD-KTs. In 2018, Spain had the highest DD-KT rate (64.6 p.m.p.) and Turkey the highest LD-KT rate (37.0 p.m.p.). Conclusions. The total KT rate increased due to a rise in the KT rate from DDs and to a lesser extent from LDs, with large differences between individual European countries.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Europe, kidney transplantation, trends
in
Nephrology Dialysis Transplantation
volume
38
issue
6
pages
12 pages
publisher
Oxford University Press
external identifiers
  • pmid:36610723
  • scopus:85160877129
ISSN
0931-0509
DOI
10.1093/ndt/gfac333
language
English
LU publication?
yes
id
07829502-eab7-46f9-ade6-9aab06b4b2a2
date added to LUP
2023-08-22 10:39:04
date last changed
2024-04-20 02:14:08
@article{07829502-eab7-46f9-ade6-9aab06b4b2a2,
  abstract     = {{<p>Background. The aim of this study was to identify trends in total, deceased donor (DD) and living donor (LD) kidney transplantation (KT) rates in European countries. Methods. The European Renal Association (ERA) Registry and the Global Observatory on Donation and Transplantation (GODT) databases were used to obtain the number of KTs in individual European countries between 2010 and 2018. General population counts were obtained from Eurostat or the national bureaus of statistics. The KT rate per million population (p.m.p.) and the average annual percentage change (APC) were calculated. Results. The total KT rate in the 40 participating countries increased with 1.9% annually [95% confidence interval (CI) 1.5, 2.2] from 29.6 p.m.p. in 2010 to 34.7 p.m.p. in 2018, reflecting an increase of 3.4 p.m.p. in the DD-KT rate (from 21.6 p.m.p. to 25.0 p.m.p.; APC 1.9%; 95% CI 1.3, 2.4) and of 1.5 p.m.p. in the LD-KT rate (from 8.1 p.m.p. to 9.6 p.m.p.; APC 1.6%; 95% CI 1.0, 2.3). The trends in KT rate varied widely across European countries. An East-West gradient was observed for DD-KT rate, with Western European countries performing more KTs. In addition, most countries performed fewer LD-KTs. In 2018, Spain had the highest DD-KT rate (64.6 p.m.p.) and Turkey the highest LD-KT rate (37.0 p.m.p.). Conclusions. The total KT rate increased due to a rise in the KT rate from DDs and to a lesser extent from LDs, with large differences between individual European countries.</p>}},
  author       = {{Boenink, Rianne and Kramer, Anneke and Tuinhout, Rosalie E. and Savoye, Emilie and Åsberg, Anders and Idrizi, Alma and Kerschbaum, Julia and Ziedina, Ieva and Ziginskiene, Edita and Farrugia, Emanuel and Garneata, Liliana and Zakharova, Elena V. and Bell, Samira and Arnol, Miha and Segelmark, Mårten and Ioannou, Kyriakos and Hommel, Kristine and Rosenberg-Ots, Mai and Vazelov, Evgueniy and Helve, Jaakko and Mihály, Sándor and Pálsson, Runólfur and Nordio, Maurizio and Gjorgjievski, Nikola and De Vries, Aiko P.J. and Seyahi, Nurhan and Magadi, Winnie A. and Resíc, Halima and Kalachyk, Aleh and Rahmel, Axel O. and Galvão, Ana A. and Naumovic, Radomir and Lundgren, Torbjörn and Arici, Mustafa and de Meester, Johan M. and Ortiz, Alberto and Jager, Kitty J. and Stel, Vianda S.}},
  issn         = {{0931-0509}},
  keywords     = {{Europe; kidney transplantation; trends}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{1528--1539}},
  publisher    = {{Oxford University Press}},
  series       = {{Nephrology Dialysis Transplantation}},
  title        = {{Trends in kidney transplantation rate across Europe : a study from the ERA Registry}},
  url          = {{http://dx.doi.org/10.1093/ndt/gfac333}},
  doi          = {{10.1093/ndt/gfac333}},
  volume       = {{38}},
  year         = {{2023}},
}