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Delivery of acute ischaemic stroke treatments in the European region in 2019 and 2020

Aguiar de Sousa, Diana ; Wilkie, Arlene ; Norrving, Bo LU ; Macey, Chris ; Bassetti, Claudio ; Tiu, Cristina ; Roth, Greg ; Lunde, Grethe ; Christensen, Hanne and Fiehler, Jens , et al. (2023) In European Stroke Journal 8(3). p.618-628
Abstract

Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020. Patients and methods: We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stroke incidence were based on United Nations data and the Global Burden of Disease Report 2019, respectively. Results: The estimated mean number of acute SUs in 2019 was 3.68 (95% CI: 2.90–4.45) per one million inhabitants (MIH) with 7/44 countries having less than one SU per one MIH. The estimated mean annual number of IVTs was 21.03 (95% CI:... (More)

Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020. Patients and methods: We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stroke incidence were based on United Nations data and the Global Burden of Disease Report 2019, respectively. Results: The estimated mean number of acute SUs in 2019 was 3.68 (95% CI: 2.90–4.45) per one million inhabitants (MIH) with 7/44 countries having less than one SU per one MIH. The estimated mean annual number of IVTs was 21.03 (95% CI: 15.63–26.43) per 100,000 and 17.14% (95% CI: 12.98–21.30) of the AIIS in 2019, with highest country rates at 79.19 and 52.66%, respectively, and 15 countries delivering less than 10 IVT per 100,000. The estimated mean annual number of EVTs in 2019 was 7.87 (95% CI: 5.96–9.77) per 100,000 and 6.91% (95% CI: 5.15–8.67) of AIIS, with 11 countries delivering less than 1.5 EVT per 100,000. Rates of SUs, IVT and EVT were stable in 2020. There was an increase in mean rates of SUs, IVT and EVT compared to similar data from 2016. Conclusion: Although there was an increase in reperfusion treatment rates in many countries between 2016 and 2019, this was halted in 2020. There are persistent major inequalities in acute stroke treatment in the European region. Tailored strategies directed to the most vulnerable regions should be prioritised.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
acute stroke treatment, endovascular treatment, Europe, health care resources, intravenous thrombolysis, stroke care implementation, stroke unit
in
European Stroke Journal
volume
8
issue
3
pages
11 pages
publisher
SAGE Publications
external identifiers
  • pmid:37431768
  • scopus:85165559753
ISSN
2396-9873
DOI
10.1177/23969873231186042
language
English
LU publication?
yes
id
07a584f8-159a-40ea-8f8f-7420f9071ec3
date added to LUP
2023-11-24 14:48:47
date last changed
2024-04-21 17:37:46
@article{07a584f8-159a-40ea-8f8f-7420f9071ec3,
  abstract     = {{<p>Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020. Patients and methods: We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stroke incidence were based on United Nations data and the Global Burden of Disease Report 2019, respectively. Results: The estimated mean number of acute SUs in 2019 was 3.68 (95% CI: 2.90–4.45) per one million inhabitants (MIH) with 7/44 countries having less than one SU per one MIH. The estimated mean annual number of IVTs was 21.03 (95% CI: 15.63–26.43) per 100,000 and 17.14% (95% CI: 12.98–21.30) of the AIIS in 2019, with highest country rates at 79.19 and 52.66%, respectively, and 15 countries delivering less than 10 IVT per 100,000. The estimated mean annual number of EVTs in 2019 was 7.87 (95% CI: 5.96–9.77) per 100,000 and 6.91% (95% CI: 5.15–8.67) of AIIS, with 11 countries delivering less than 1.5 EVT per 100,000. Rates of SUs, IVT and EVT were stable in 2020. There was an increase in mean rates of SUs, IVT and EVT compared to similar data from 2016. Conclusion: Although there was an increase in reperfusion treatment rates in many countries between 2016 and 2019, this was halted in 2020. There are persistent major inequalities in acute stroke treatment in the European region. Tailored strategies directed to the most vulnerable regions should be prioritised.</p>}},
  author       = {{Aguiar de Sousa, Diana and Wilkie, Arlene and Norrving, Bo and Macey, Chris and Bassetti, Claudio and Tiu, Cristina and Roth, Greg and Lunde, Grethe and Christensen, Hanne and Fiehler, Jens and Pezzella, Francesca Romana and Dichgans, Martin and Roaldsen, Melinda B. and Kelly, Peter and Mikulik, Robert and Sacco, Simona and Caso, Valeria and Fischer, Urs}},
  issn         = {{2396-9873}},
  keywords     = {{acute stroke treatment; endovascular treatment; Europe; health care resources; intravenous thrombolysis; stroke care implementation; stroke unit}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{618--628}},
  publisher    = {{SAGE Publications}},
  series       = {{European Stroke Journal}},
  title        = {{Delivery of acute ischaemic stroke treatments in the European region in 2019 and 2020}},
  url          = {{http://dx.doi.org/10.1177/23969873231186042}},
  doi          = {{10.1177/23969873231186042}},
  volume       = {{8}},
  year         = {{2023}},
}