Functional hearing deficits in children with Type 1 diabetes
(2016) In Diabetic Medicine 33(9). p.1268-1274- Abstract
Aim: Hearing loss (as reflected by abnormal sound detection) is a frequently reported consequence of Type 1 diabetes mellitus. We sought to evaluate sound detection, auditory neural function and binaural processing ability in a group of school-aged participants with Type 1 diabetes and to assess their functional hearing and general communication ability. Methods: A range of electroacoustic, electrophysiological and behavioural test techniques were used to evaluate both cochlear and auditory neural function in 19 affected children. A cohort of matched controls was also assessed. Results: Although all of the participants with Type 1 diabetes enjoyed normal sound detection, 9 of the 19 (47%) showed evidence of auditory pathway abnormality... (More)
Aim: Hearing loss (as reflected by abnormal sound detection) is a frequently reported consequence of Type 1 diabetes mellitus. We sought to evaluate sound detection, auditory neural function and binaural processing ability in a group of school-aged participants with Type 1 diabetes and to assess their functional hearing and general communication ability. Methods: A range of electroacoustic, electrophysiological and behavioural test techniques were used to evaluate both cochlear and auditory neural function in 19 affected children. A cohort of matched controls was also assessed. Results: Although all of the participants with Type 1 diabetes enjoyed normal sound detection, 9 of the 19 (47%) showed evidence of auditory pathway abnormality with evoked potential latencies and/or amplitudes beyond age-related norms. Auditory brainstem response interpeak latencies (wave I-V) were longer than in matched controls [ 95% confidence interval (95% CI); 0.10, 0.28 ms: P <0.001] and wave V amplitudes were reduced (95% CI; -0.21, 0.00 μV: P = 0.02). Binaural speech perception in noise was also impaired (95% CI; 0.82, 3.17 dB: P = 0.002) and perceptual ability was correlated with degree of neural disruption in the auditory brainstem (r = 0.662, P = 0.003). Conclusions: Hearing deficits severe enough to restrict communication and threaten academic progress were common on our group of school-aged children with Type 1 diabetes. Evaluation of both cochlear and auditory neural function may form an important part of the standard management regime for children with diabetes.
(Less)
- author
- Rance, G. ; Chisari, D. ; Edvall, Niklas and Cameron, F.
- organization
- publishing date
- 2016-02-16
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Diabetic Medicine
- volume
- 33
- issue
- 9
- pages
- 1268 - 1274
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000383280100015
- pmid:26823194
- scopus:84982300248
- ISSN
- 0742-3071
- DOI
- 10.1111/dme.13086
- language
- English
- LU publication?
- no
- id
- 0bdaecf5-b05f-4e5f-8df7-5b4e944a1c03
- date added to LUP
- 2016-05-13 12:06:22
- date last changed
- 2022-04-08 21:01:19
@article{0bdaecf5-b05f-4e5f-8df7-5b4e944a1c03, abstract = {{<p>Aim: Hearing loss (as reflected by abnormal sound detection) is a frequently reported consequence of Type 1 diabetes mellitus. We sought to evaluate sound detection, auditory neural function and binaural processing ability in a group of school-aged participants with Type 1 diabetes and to assess their functional hearing and general communication ability. Methods: A range of electroacoustic, electrophysiological and behavioural test techniques were used to evaluate both cochlear and auditory neural function in 19 affected children. A cohort of matched controls was also assessed. Results: Although all of the participants with Type 1 diabetes enjoyed normal sound detection, 9 of the 19 (47%) showed evidence of auditory pathway abnormality with evoked potential latencies and/or amplitudes beyond age-related norms. Auditory brainstem response interpeak latencies (wave I-V) were longer than in matched controls [ 95% confidence interval (95% CI); 0.10, 0.28 ms: P <0.001] and wave V amplitudes were reduced (95% CI; -0.21, 0.00 μV: P = 0.02). Binaural speech perception in noise was also impaired (95% CI; 0.82, 3.17 dB: P = 0.002) and perceptual ability was correlated with degree of neural disruption in the auditory brainstem (r = 0.662, P = 0.003). Conclusions: Hearing deficits severe enough to restrict communication and threaten academic progress were common on our group of school-aged children with Type 1 diabetes. Evaluation of both cochlear and auditory neural function may form an important part of the standard management regime for children with diabetes.</p>}}, author = {{Rance, G. and Chisari, D. and Edvall, Niklas and Cameron, F.}}, issn = {{0742-3071}}, language = {{eng}}, month = {{02}}, number = {{9}}, pages = {{1268--1274}}, publisher = {{Wiley-Blackwell}}, series = {{Diabetic Medicine}}, title = {{Functional hearing deficits in children with Type 1 diabetes}}, url = {{http://dx.doi.org/10.1111/dme.13086}}, doi = {{10.1111/dme.13086}}, volume = {{33}}, year = {{2016}}, }