Andrologisk undersökning bör ingå i infertilitetsutredningen
(2022) In Lakartidningen 119.- Abstract
Impaired semen quality is present in approximately 50% of all infertile couples, indicating decreased fertility in the male. The etiology is unknown in 40-60% of the cases and standard semen parameters provide limited information about the cause and the chance for pregnancy in vivo or in vitro. Assessment of sperm DNA strand breaks may therefore be useful for optimal infertility treatment. Since the causes of infertility of the male part are largely unknown, few options for treatment of decreased semen quality are at hand. This applies to pharmacological and surgical methods as well as lifestyle related interventions. There are studies showing that infertile men have a significant risk of hypogonadism and shorter life expectancy due to... (More)
Impaired semen quality is present in approximately 50% of all infertile couples, indicating decreased fertility in the male. The etiology is unknown in 40-60% of the cases and standard semen parameters provide limited information about the cause and the chance for pregnancy in vivo or in vitro. Assessment of sperm DNA strand breaks may therefore be useful for optimal infertility treatment. Since the causes of infertility of the male part are largely unknown, few options for treatment of decreased semen quality are at hand. This applies to pharmacological and surgical methods as well as lifestyle related interventions. There are studies showing that infertile men have a significant risk of hypogonadism and shorter life expectancy due to higher risk of cardiovascular and metabolic diseases as well as certain cancers. Poor fertility can hence be considered as an early marker of general disease. Andrological examination, not only limited to semen analysis, but also including clinical, endocrinological and in some cases genetic evaluation should be part of the routine work-up of infertile couples.
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- author
- Elenkov, Angel LU ; Lundberg Giwercman, Yvonne LU and Giwercman, Aleksander LU
- organization
- alternative title
- Andrological aspects of infertility
- publishing date
- 2022-12-14
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Lakartidningen
- volume
- 119
- publisher
- Swedish Medical Association
- external identifiers
-
- scopus:85144585088
- pmid:36519707
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- yes
- id
- 0e91d8e2-c3df-45f4-bc67-abfd81d58a46
- date added to LUP
- 2023-01-16 08:59:56
- date last changed
- 2024-06-27 02:56:41
@article{0e91d8e2-c3df-45f4-bc67-abfd81d58a46,
abstract = {{<p>Impaired semen quality is present in approximately 50% of all infertile couples, indicating decreased fertility in the male. The etiology is unknown in 40-60% of the cases and standard semen parameters provide limited information about the cause and the chance for pregnancy in vivo or in vitro. Assessment of sperm DNA strand breaks may therefore be useful for optimal infertility treatment. Since the causes of infertility of the male part are largely unknown, few options for treatment of decreased semen quality are at hand. This applies to pharmacological and surgical methods as well as lifestyle related interventions. There are studies showing that infertile men have a significant risk of hypogonadism and shorter life expectancy due to higher risk of cardiovascular and metabolic diseases as well as certain cancers. Poor fertility can hence be considered as an early marker of general disease. Andrological examination, not only limited to semen analysis, but also including clinical, endocrinological and in some cases genetic evaluation should be part of the routine work-up of infertile couples.</p>}},
author = {{Elenkov, Angel and Lundberg Giwercman, Yvonne and Giwercman, Aleksander}},
issn = {{0023-7205}},
language = {{swe}},
month = {{12}},
publisher = {{Swedish Medical Association}},
series = {{Lakartidningen}},
title = {{Andrologisk undersökning bör ingå i infertilitetsutredningen}},
volume = {{119}},
year = {{2022}},
}