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Stable population-based incidence of acute type A and B aortic dissection

Acosta, Stefan LU and Gottsäter, Anders LU (2019) In Scandinavian Cardiovascular Journal 53(5). p.274-279
Abstract

Background. Aortic dissection (AD) and abdominal aortic aneurysm (AAA) share the same risk factors. Whereas the incidence of AAA is falling, it is unclear whether population-based incidences of acute type A and B AD have changed. The aim of this study was to investigate incidences of AD subtypes over time. Methods. Citizens in the municipality of Malmö, Sweden, diagnosed with AD in 2000–2004 and 2014–2016 were identified through the in-patient, clinical, and forensic autopsy registers. Results. The overall and gender-specific incidences of acute type A and B AD were stable over time. The overall autopsy rate declined from 25.2% in 2000–2004 to 16.1% in 2014–2016 (p =.0001) and patients with acute type A AD were more often encountered at... (More)

Background. Aortic dissection (AD) and abdominal aortic aneurysm (AAA) share the same risk factors. Whereas the incidence of AAA is falling, it is unclear whether population-based incidences of acute type A and B AD have changed. The aim of this study was to investigate incidences of AD subtypes over time. Methods. Citizens in the municipality of Malmö, Sweden, diagnosed with AD in 2000–2004 and 2014–2016 were identified through the in-patient, clinical, and forensic autopsy registers. Results. The overall and gender-specific incidences of acute type A and B AD were stable over time. The overall autopsy rate declined from 25.2% in 2000–2004 to 16.1% in 2014–2016 (p =.0001) and patients with acute type A AD were more often encountered at autopsy (78% of cases) during the first time period, compared to 43% of cases during the second time period (p =.005), when the ratio of acute type A: acute type B AD was 2.6: 1. The proportion of individuals <65 years of age tended to be higher in acute type A AD compared to acute type B AD (p =.07). The frequencies of hypertension and smoking were 90% and 91%, respectively, in type A AD, and 86% and 86%, respectively in type B AD. Conclusions. Population-based incidences of acute type A and type B AD were stable over time, but the decreasing autopsy rate has led to a lower proportion of AD diagnosed at autopsy. Primary prevention towards hypertension and smoking seem necessary to reduce AD incidence.

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author
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type
Contribution to journal
publication status
published
subject
keywords
Acute aortic dissection, incidence, mortality, type A aortic dissection, type B aortic dissection
in
Scandinavian Cardiovascular Journal
volume
53
issue
5
pages
6 pages
publisher
Taylor & Francis
external identifiers
  • scopus:85071709216
  • pmid:31290700
ISSN
1401-7431
DOI
10.1080/14017431.2019.1642509
language
English
LU publication?
yes
id
0f654f1b-f60c-4f6a-a48b-f9fcb4d9fe5e
date added to LUP
2019-09-17 08:46:41
date last changed
2020-11-16 03:08:58
@article{0f654f1b-f60c-4f6a-a48b-f9fcb4d9fe5e,
  abstract     = {<p>Background. Aortic dissection (AD) and abdominal aortic aneurysm (AAA) share the same risk factors. Whereas the incidence of AAA is falling, it is unclear whether population-based incidences of acute type A and B AD have changed. The aim of this study was to investigate incidences of AD subtypes over time. Methods. Citizens in the municipality of Malmö, Sweden, diagnosed with AD in 2000–2004 and 2014–2016 were identified through the in-patient, clinical, and forensic autopsy registers. Results. The overall and gender-specific incidences of acute type A and B AD were stable over time. The overall autopsy rate declined from 25.2% in 2000–2004 to 16.1% in 2014–2016 (p =.0001) and patients with acute type A AD were more often encountered at autopsy (78% of cases) during the first time period, compared to 43% of cases during the second time period (p =.005), when the ratio of acute type A: acute type B AD was 2.6: 1. The proportion of individuals &lt;65 years of age tended to be higher in acute type A AD compared to acute type B AD (p =.07). The frequencies of hypertension and smoking were 90% and 91%, respectively, in type A AD, and 86% and 86%, respectively in type B AD. Conclusions. Population-based incidences of acute type A and type B AD were stable over time, but the decreasing autopsy rate has led to a lower proportion of AD diagnosed at autopsy. Primary prevention towards hypertension and smoking seem necessary to reduce AD incidence.</p>},
  author       = {Acosta, Stefan and Gottsäter, Anders},
  issn         = {1401-7431},
  language     = {eng},
  number       = {5},
  pages        = {274--279},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Cardiovascular Journal},
  title        = {Stable population-based incidence of acute type A and B aortic dissection},
  url          = {http://dx.doi.org/10.1080/14017431.2019.1642509},
  doi          = {10.1080/14017431.2019.1642509},
  volume       = {53},
  year         = {2019},
}