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Quality of life in oral carcinoma: A 5-year prospective study.

Nordgren, Mats LU ; Hammerlid, Eva; Bjordal, Kristin; Ahlner-Elmqvist, Marianne LU ; Boysen, Morten and Jannert, Magnus LU (2008) In Head and Neck 30(4). p.461-470
Abstract
BACKGROUND.: We conducted this prospective longitudinal multicenter study to evaluate the health-related quality of life (HRQL) of patients with oral carcinoma at diagnosis, and after 1 and 5 years in relation to tumour location and treatment modality. METHODS.: One hundred twenty-two patients (mean age, 61; 62% males) with oral carcinoma were evaluated with standardized HRQL questionnaires, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core30 (EORTC QLQ-C30) and the EORTC Head and Neck Cancer Module (EORTC QLQ-H&N35). RESULTS.: Problems with teeth, dry mouth, and sticky saliva got worse between diagnosis and 5 years after diagnosis. Problems with dry mouth remained a problem between 1 and... (More)
BACKGROUND.: We conducted this prospective longitudinal multicenter study to evaluate the health-related quality of life (HRQL) of patients with oral carcinoma at diagnosis, and after 1 and 5 years in relation to tumour location and treatment modality. METHODS.: One hundred twenty-two patients (mean age, 61; 62% males) with oral carcinoma were evaluated with standardized HRQL questionnaires, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core30 (EORTC QLQ-C30) and the EORTC Head and Neck Cancer Module (EORTC QLQ-H&N35). RESULTS.: Problems with teeth, dry mouth, and sticky saliva got worse between diagnosis and 5 years after diagnosis. Problems with dry mouth remained a problem between 1 and 5 years after diagnosis, except for the patients treated with surgery only. This group had fewer problems over time compared with patients receiving other treatment regimes. Survivors reported better HRQL than the nonsurvivors at diagnosis and at the 1-year follow-up. HRQL at diagnosis was associated with survival. CONCLUSIONS.: HRQL at diagnosis for patients with oral carcinoma seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of oral carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and sticky saliva. (c) 2007 Wiley Periodicals, Inc. Head Neck, 2008. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Head and Neck
volume
30
issue
4
pages
461 - 470
publisher
John Wiley & Sons
external identifiers
  • pmid:18098303
  • wos:000254689800006
  • scopus:42549107273
ISSN
1043-3074
DOI
10.1002/hed.20735
language
English
LU publication?
yes
id
26520d63-ea97-4db3-a70f-4d4ac1d79ea8 (old id 1034993)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18098303?dopt=Abstract
date added to LUP
2009-07-10 16:42:12
date last changed
2017-09-24 03:41:03
@article{26520d63-ea97-4db3-a70f-4d4ac1d79ea8,
  abstract     = {BACKGROUND.: We conducted this prospective longitudinal multicenter study to evaluate the health-related quality of life (HRQL) of patients with oral carcinoma at diagnosis, and after 1 and 5 years in relation to tumour location and treatment modality. METHODS.: One hundred twenty-two patients (mean age, 61; 62% males) with oral carcinoma were evaluated with standardized HRQL questionnaires, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core30 (EORTC QLQ-C30) and the EORTC Head and Neck Cancer Module (EORTC QLQ-H&N35). RESULTS.: Problems with teeth, dry mouth, and sticky saliva got worse between diagnosis and 5 years after diagnosis. Problems with dry mouth remained a problem between 1 and 5 years after diagnosis, except for the patients treated with surgery only. This group had fewer problems over time compared with patients receiving other treatment regimes. Survivors reported better HRQL than the nonsurvivors at diagnosis and at the 1-year follow-up. HRQL at diagnosis was associated with survival. CONCLUSIONS.: HRQL at diagnosis for patients with oral carcinoma seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of oral carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and sticky saliva. (c) 2007 Wiley Periodicals, Inc. Head Neck, 2008.},
  author       = {Nordgren, Mats and Hammerlid, Eva and Bjordal, Kristin and Ahlner-Elmqvist, Marianne and Boysen, Morten and Jannert, Magnus},
  issn         = {1043-3074},
  language     = {eng},
  number       = {4},
  pages        = {461--470},
  publisher    = {John Wiley & Sons},
  series       = {Head and Neck},
  title        = {Quality of life in oral carcinoma: A 5-year prospective study.},
  url          = {http://dx.doi.org/10.1002/hed.20735},
  volume       = {30},
  year         = {2008},
}