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Sequelae following sural nerve biopsy in type 1 diabetic subjects.

Dahlin, Lars LU ; Lithner, F; Bresäter, L-E; Thomsen, Niels LU ; Eriksson, Karl-Fredrik LU and Sundkvist, Göran LU (2008) In Acta Neurologica Scandinavica 118. p.193-197
Abstract
Objectives - To detect post-operative sequelae of sural nerve biopsy. Materials and methods-- A questionnaire mailed to type 1 diabetic patients (n = 24; male/female 23/1; reply n = 23) 2 years after biopsy. Results - Type 1 diabetic patients (age 56 [11]; median [interquartile range]) had a long duration of diabetes (DM; 20 [19] years) and all had neuropathy. Three out of 24 patients developed infection (two superficial and one deep) and one had a post-operative bleeding. Less frequent pain among the patients were reported from one centre. About one-third or more of the patients still complained of pain, mostly mild, in the biopsy area and paraesthesia in the foot 2 years after surgery. More than two-thirds of the patients were reluctant... (More)
Objectives - To detect post-operative sequelae of sural nerve biopsy. Materials and methods-- A questionnaire mailed to type 1 diabetic patients (n = 24; male/female 23/1; reply n = 23) 2 years after biopsy. Results - Type 1 diabetic patients (age 56 [11]; median [interquartile range]) had a long duration of diabetes (DM; 20 [19] years) and all had neuropathy. Three out of 24 patients developed infection (two superficial and one deep) and one had a post-operative bleeding. Less frequent pain among the patients were reported from one centre. About one-third or more of the patients still complained of pain, mostly mild, in the biopsy area and paraesthesia in the foot 2 years after surgery. More than two-thirds of the patients were reluctant for further biopsy; a crucial information in drug trial planning. Conclusions - Sequelae of a sural nerve biopsy occur in type 1 DM. The risk for wound infections should be considered. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Neurologica Scandinavica
volume
118
pages
193 - 197
publisher
Wiley-Blackwell
external identifiers
  • PMID:18336622
  • WOS:000258376100009
  • Scopus:49649109583
ISSN
1600-0404
DOI
10.1111/j.1600-0404.2008.01000.x
language
English
LU publication?
yes
id
b73c9735-64ca-4e5f-96ef-270f1b76e71d (old id 1052503)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18336622?dopt=Abstract
date added to LUP
2008-04-01 10:55:36
date last changed
2017-01-01 07:42:46
@article{b73c9735-64ca-4e5f-96ef-270f1b76e71d,
  abstract     = {Objectives - To detect post-operative sequelae of sural nerve biopsy. Materials and methods-- A questionnaire mailed to type 1 diabetic patients (n = 24; male/female 23/1; reply n = 23) 2 years after biopsy. Results - Type 1 diabetic patients (age 56 [11]; median [interquartile range]) had a long duration of diabetes (DM; 20 [19] years) and all had neuropathy. Three out of 24 patients developed infection (two superficial and one deep) and one had a post-operative bleeding. Less frequent pain among the patients were reported from one centre. About one-third or more of the patients still complained of pain, mostly mild, in the biopsy area and paraesthesia in the foot 2 years after surgery. More than two-thirds of the patients were reluctant for further biopsy; a crucial information in drug trial planning. Conclusions - Sequelae of a sural nerve biopsy occur in type 1 DM. The risk for wound infections should be considered.},
  author       = {Dahlin, Lars and Lithner, F and Bresäter, L-E and Thomsen, Niels and Eriksson, Karl-Fredrik and Sundkvist, Göran},
  issn         = {1600-0404},
  language     = {eng},
  pages        = {193--197},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Neurologica Scandinavica},
  title        = {Sequelae following sural nerve biopsy in type 1 diabetic subjects.},
  url          = {http://dx.doi.org/10.1111/j.1600-0404.2008.01000.x},
  volume       = {118},
  year         = {2008},
}