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Distribution of pancreatic polypeptide and peptide YY.

Ekblad, Eva LU and Sundler, Frank LU (2002) In Peptides 23(2). p.251-261
Abstract
The cellular distribution of PP and PYY in mammals is reviewed. Expression of PP is restricted to endocrine cells mainly present in the pancreas predominantly in the duodenal portion (head) but also found in small numbers in the gastro-intestinal tract. PYY has a dual expression in both endocrine cells and neurons. PYY expressing endocrine cells occur all along the gastrointestinal tract and are frequent in the distal portion. Islet cells expressing PYY are found in many species. In rodents they predominate in the splenic portion (tail) of the pancreas. A limited expression of PYY is found also in endocrine cells in the adrenal gland, respiratory tract and pituitary. Peripheral, particularly enteric, neurons also express PYY as does a... (More)
The cellular distribution of PP and PYY in mammals is reviewed. Expression of PP is restricted to endocrine cells mainly present in the pancreas predominantly in the duodenal portion (head) but also found in small numbers in the gastro-intestinal tract. PYY has a dual expression in both endocrine cells and neurons. PYY expressing endocrine cells occur all along the gastrointestinal tract and are frequent in the distal portion. Islet cells expressing PYY are found in many species. In rodents they predominate in the splenic portion (tail) of the pancreas. A limited expression of PYY is found also in endocrine cells in the adrenal gland, respiratory tract and pituitary. Peripheral, particularly enteric, neurons also express PYY as does a restricted set of central neurons. (Less)
Please use this url to cite or link to this publication:
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Contribution to journal
publication status
published
subject
keywords
Endocrine Glands/metabolism, Human, Microscopy, Fluorescence, Neurons/metabolism, Pancreas/*metabolism, Pancreatic Polypeptide/*biosynthesis, Peptide YY/*metabolism, Respiratory System/metabolism, Rats, Animal, Spleen/metabolism, Support, Non-U.S. Gov't, Adrenal Glands/metabolism
in
Peptides
volume
23
issue
2
pages
251 - 261
publisher
Elsevier
external identifiers
  • pmid:11825640
  • wos:000173907700002
  • scopus:0036161876
ISSN
1873-5169
DOI
10.1016/S0196-9781(01)00601-5
language
English
LU publication?
yes
id
0d688188-6489-4b78-83ef-79e244e43ed1 (old id 106223)
alternative location
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11825640&dopt=Abstract
date added to LUP
2007-07-11 14:44:27
date last changed
2017-12-10 03:51:04
@article{0d688188-6489-4b78-83ef-79e244e43ed1,
  abstract     = {The cellular distribution of PP and PYY in mammals is reviewed. Expression of PP is restricted to endocrine cells mainly present in the pancreas predominantly in the duodenal portion (head) but also found in small numbers in the gastro-intestinal tract. PYY has a dual expression in both endocrine cells and neurons. PYY expressing endocrine cells occur all along the gastrointestinal tract and are frequent in the distal portion. Islet cells expressing PYY are found in many species. In rodents they predominate in the splenic portion (tail) of the pancreas. A limited expression of PYY is found also in endocrine cells in the adrenal gland, respiratory tract and pituitary. Peripheral, particularly enteric, neurons also express PYY as does a restricted set of central neurons.},
  author       = {Ekblad, Eva and Sundler, Frank},
  issn         = {1873-5169},
  keyword      = {Endocrine Glands/metabolism,Human,Microscopy,Fluorescence,Neurons/metabolism,Pancreas/*metabolism,Pancreatic Polypeptide/*biosynthesis,Peptide YY/*metabolism,Respiratory System/metabolism,Rats,Animal,Spleen/metabolism,Support,Non-U.S. Gov't,Adrenal Glands/metabolism},
  language     = {eng},
  number       = {2},
  pages        = {251--261},
  publisher    = {Elsevier},
  series       = {Peptides},
  title        = {Distribution of pancreatic polypeptide and peptide YY.},
  url          = {http://dx.doi.org/10.1016/S0196-9781(01)00601-5},
  volume       = {23},
  year         = {2002},
}